ArticlePlanta2007
NADPH recycling systems in oxidative stressed pea nodules: a key role for the NADP+ -dependent isocitrate dehydrogenase.
Article in Planta, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 65 citations in OpenAlex.
- Responsivity of Two Pea Genotypes to the Symbiosis with Rhizobia and Arbuscular Mycorrhiza Fungi-A Proteomics Aspect of the "Efficiency of Interactions with Beneficial Soil Microorganisms" Trait.International journal of molecular sciences · 2025Article
- Characterization of the Isocitrate Dehydrogenase Gene Family and Their Response to Drought Stress in Maize.Plants (Basel, Switzerland) · 2023Article
- TransgenicFrontiers in plant science · 2022Article
- Exogenous CaPlanta · 2021Article
- BRS1 mediates plant redox regulation and cold responses.BMC plant biology · 2021Article
- Cadmium-Tolerant and -Sensitive Cultivars Identified by Screening ofFrontiers in plant science · 2021Article
- Redox status regulates subcelluar localization of PpTGA1 associated with a BABA-induced priming defence against Rhizopus rot in peach fruit.Molecular biology reports · 2020Article
- Short-Term Low Temperature Induces Nitro-Oxidative Stress that Deregulates the NADP-Malic Enzyme Function by Tyrosine Nitration inAntioxidants (Basel, Switzerland) · 2019Article
- NADPH ameliorates MPTP-induced dopaminergic neurodegeneration through inhibiting p38MAPK activation.Acta pharmacologica Sinica · 2019Article
- Rosmarinic acid induces programmed cell death in Arabidopsis seedlings through reactive oxygen species and mitochondrial dysfunction.PloS one · 2018Article
- PhoU2 but Not PhoU1 as an Important Regulator of Biofilm Formation and Tolerance to Multiple Stresses by Participating in Various Fundamental Metabolic Processes in Staphylococcus epidermidis.Journal of bacteriology · 2017Article
- Molecular mechanism of the allosteric regulation of the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase.Scientific reports · 2017Article
- Nitrogen Source and External Medium pH Interaction Differentially Affects Root and Shoot Metabolism in Arabidopsis.Frontiers in plant science · 2016Article
- Physiological and proteomic alterations in rice (Oryza sativa L.) seedlings under hexavalent chromium stress.Planta · 2014Article
- Protein tyrosine nitration in pea roots during development and senescence.Journal of experimental botany · 2013Article
- Molecular mechanisms of desiccation tolerance in the resurrection glacial relic Haberlea rhodopensis.Cellular and molecular life sciences : CMLS · 2013Article
- Proteomic profiling of Rhizobium tropici PRF 81: identification of conserved and specific responses to heat stress.BMC microbiology · 2012Article
- NADP-dependent isocitrate dehydrogenase from Arabidopsis roots contributes in the mechanism of defence against the nitro-oxidative stress induced by salinity.TheScientificWorldJournal · 2012Article
- Peroxiredoxins and NADPH-dependent thioredoxin systems in the model legume Lotus japonicus.Plant physiology · 2011Article
- Role of plant glyoxylate reductases during stress: a hypothesis.The Biochemical journal · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The symbiosis between legumes and rhizobia is characterised by the formation of dinitrogen-fixing root nodules. In natural conditions, nitrogen fixation is strongly impaired by abiotic stresses which generate over-production of reactive oxygen species. Since one of the nodule main antioxidant systems is the ascorbate-glutathione cycle, NADPH recycling that is involved in glutathione reduction is of great relevance under stress conditions. NADPH is mainly produced by glucose 6-phosphate dehydrogenase (G6PDH; EC 1.1.1.49) and 6-phosphogluconate dehydrogenase (6PGDH; EC 1.1.1.44) from the oxidative pentose phosphate pathway, and also by NADP(+)-dependent isocitrate dehydrogenase (ICDH; EC 1.1.1.42). In this work, 10 microM paraquat (PQ) was applied to pea roots in order to determine the in vivo relationship between oxidative stress and the activity of the NADPH-generating enzymes in nodules. Whereas G6PDH and 6PGDH activities remained unchanged, a remarkable induction of ICDH gene expression and a dramatic increase of the ICDH activity was observed during the PQ treatment. These results support that ICDH has a key role in NADPH recycling under oxidative stress conditions in pea root nodules.
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