Evidence map›Paper›PMID 16896724›Full record

Trial reportEuropean journal of applied physiology2006

Effect of multiple oral doses of androgenic anabolic steroids on endurance performance and serum indices of physical stress in healthy male subjects.

Norbert Baume, Yorck Olaf Schumacher, Pierre-Edouard Sottas, Carlo Bagutti, Michel Cauderay, Patrice Mangin, Martial Saugy

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Guideline
  2. Article
  3. The assessment of liver function test and fertility hormones in Saudi athletes using anabolic androgenic steroids.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2024
    Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Long-term anabolic steroids in male bodybuilders induce cardiovascular structural and autonomic abnormalities.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2018
    Article
  9. Sport and male sexuality.Journal of endocrinological investigation · 2017
    Review
  10. Review
  11. Review
  12. Article
  13. The role of human body movements in mate selection.Evolutionary psychology : an international journal of evolutionary approaches to psychology and behavior · 2010
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Norbert BaumeLaboratoire Suisse d'Analyse du Dopage, Institut Universitaire de Médecine Légale, Ch. des Croisettes 22, 1066, Epalinges, Switzerland. norbaume@gmail.com
Yorck Olaf Schumacher
Pierre-Edouard Sottas
Carlo Bagutti
Michel Cauderay
Patrice Mangin
Martial Saugy
Centre Médical de Vidy · CHHôpital Riviera-Chablais · CHService Régional Vaudois de Transfusion Sanguine · CHUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anabolic androgenic steroids (AAS) are doping agents that are mostly used for improvement of strength and muscle hypertrophy. In some sports, athletes reported that the intake of AAS is associated with a better recovery, a higher training load capacity and therefore an increase in physical and mental performances. The purpose of this study was to evaluate, the effect of multiple doses of AAS on different physiological parameters that could indirectly relate the physical state of athletes during a hard endurance training program. In a double blind settings, three groups (n = 9, 8 and 8) were orally administered placebo, testosterone undecanoate or 19-norandrostenedione, 12 times during 1 month. Serum biomarkers (creatine kinase, ASAT and urea), serum hormone profiles (testosterone, cortisol and LH) and urinary catecholamines (noradrenalin, adrenalin and dopamine) were evaluated during the treatment. Running performance was assessed before and after the intervention phase by means of a standardized treadmill test. None of the measured biochemical variables showed significant impact of AAS on physical stress level. Data from exercise testing on submaximal and maximal level did not reveal any performance differences between the three groups or their response to the treatment. In the present study, no effect of multiple oral doses of AAS on endurance performance or bioserum recovery markers was found.

Indexed as

AdultAnabolic AgentsAndrogensAndrostenedioneBiomarkersCatecholaminesDouble-Blind MethodExercise TestHeart RateHormonesHumansHydrocortisoneLactic AcidMalePhysical EndurancePhysical Fitness19-norandrostenedioneAnabolic AgentsAndrogensAndrostenedioneBiomarkersCatecholaminesHormonesHydrocortisoneLactic AcidSteroidsTestosterone

Identifiers

PMID16896724
OpenAlexW2154343358

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.