Evidence map›Paper›PMID 16896649›Full record

ArticleParasitology research2007

Usefulness of Toxoplasma gondii recombinant antigens (GRA1, GRA7 and SAG1) in an immunoglobulin G avidity test for the serodiagnosis of toxoplasmosis.

H Pietkiewicz, E Hiszczyńska-Sawicka, J Kur, E Petersen, H V Nielsen, M Paul, M Stankiewicz, P Myjak

Abstract read
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In one paragraph

Article in Parasitology research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Descriptive Comparison of ELISAs for the Detection ofPathogens (Basel, Switzerland) · 2021
    Review
  6. Article
  7. Pathogens (Basel, Switzerland) · 2020
    Article
  8. Review on the Current Trends of Toxoplasmosis Serodiagnosis in Humans.Frontiers in cellular and infection microbiology · 2020
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 4 countries.

H PietkiewiczDepartment of Tropical Parasitology, Inter-Faculty Institute of Maritime and Tropical Medicine, Medical University of Gdańsk, ul. Powstania Styczniowego 9b, Gdynia, Poland.
E Hiszczyńska-Sawicka
J Kur
E Petersen
H V Nielsen
M Paul
M Stankiewicz
P Myjak
Gdańsk Medical University · PLGdańsk University of Technology · PLAarhus University Hospital · DKLincoln University · NZPoznan University of Medical Sciences · PLStatens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The precise diagnosis of an acute and recent Toxoplasma infection in pregnant women and the newborn child is important before treatment. This study describes a new Toxoplasma gondii IgG avidity test based on a combination of recombinant GRA1, GRA7 and SAG1 antigens and shows that this test is useful for diagnostic purposes and may replace the lysed, whole-cell antigens. Although more sera need to be tested, the results obtained here suggest that the IgG avidity test performed with rec-antigens correlated more with the stage of a T. gondii infection than the IgG avidity results obtained with the lysed, whole-cell antigen test, the VIDAS Toxo IgG avidity (bioMérieux).

Indexed as

AnimalsAntibody AffinityAntigens, ProtozoanImmunoglobulin GProtozoan ProteinsSensitivity and SpecificitySerologic TestsToxoplasmaToxoplasmosisAntigens, ProtozoanGRA1 antigenGRA7 protein, Toxoplasma gondiiImmunoglobulin GProtozoan ProteinsSAG1 antigen, Toxoplasma

Identifiers

PMID16896649
OpenAlexW2073166266

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.