ArticleMarine biotechnology (New York, N.Y.)
Analysis of expressed sequence tags from the harmful alga, Prymnesium parvum (Prymnesiophyceae, Haptophyta).
Article in Marine biotechnology (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 42 citations in OpenAlex.
- The Chemistry of Phytoplankton.Chemical reviews · 2024Review
- Carbohydrate-Containing Low Molecular Weight Metabolites of Microalgae.Marine drugs · 2023Review
- Insights into ToxicToxins · 2023Review
- Gene expression in the mixotrophic prymnesiophyte, Prymnesium parvum, responds to prey availability.Frontiers in microbiology · 2015Article
- Changes in gene expression of Prymnesium parvum induced by nitrogen and phosphorus limitation.Frontiers in microbiology · 2015Article
- Analysis of immune-related ESTs and differential expression analysis of few important genes in lines of rohu (Labeo rohita) selected for resistance and susceptibility to Aeromonas hydrophila infection.Molecular biology reports · 2014Article
- Article
- Progress in understanding harmful algal blooms: paradigm shifts and new technologies for research, monitoring, and management.Annual review of marine science · 2012Review
- Prymnesins: toxic metabolites of the golden alga, Prymnesium parvum Carter (Haptophyta).Marine drugs · 2010Review
- Generation and analysis of expressed sequence tags from a cDNA library of the fruiting body of Ganoderma lucidum.Chinese medicine · 2010Article
- Generation and analysis of expressed sequence tags from the ciliate protozoan parasite Ichthyophthirius multifiliis.BMC genomics · 2007Article
- Functional annotation and analysis of expressed sequence tags from the hepatopancreas of mitten crab (Eriocheir sinensis).Marine biotechnology (New York, N.Y.)Article
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1 author at 1 institution in 1 country.
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Abstract
A cDNA library was constructed from late log-phase cultures of the ichthyotoxin-producing haptophyte, Prymnesium parvum. Approximately 6,300 single-pass 5' nucleotide sequences (out of nearly 8,000 randomly isolated clones) achieved length and quality criteria for incorporation into an expressed sequence tag (EST) database. Collectively, 3,415 unique genes (tentative unigenes [TUGs]) were assembled. Database searches revealed approximately 1,100 TUG (34%) that encode proteins of known or putative function (expect values E < or = 1.0 x 10(-10)), representing most functional classes of proteins and many metabolic pathways. In addition to proteins involved in photosynthesis and protein synthesis/degradation, one of the most frequently encountered transcripts putatively encodes an ABC-type phosphate transport system component. Active (and efficient?) phosphate transport may correlate with rapid growth, perhaps explaining how this alga out-competes other species when it blooms and becomes toxic under low-phosphate conditions. The majority of TUGs, including 12 of the 50 most commonly encountered transcripts, encode potentially novel proteins, some of which are probably involved in synthesis and secretion of the unique prymnesin toxins. This work suggests that future studies on the expression of many of these genes during rapid growth should provide insight into the genetic basis of bloom formation and toxicity.
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