ArticleProceedings of the National Academy of Sciences of the United States of America2006
Phosphate acquisition genes in Prochlorococcus ecotypes: evidence for genome-wide adaptation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers.
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144 citing papers in PubMed, 329 citations in OpenAlex.
- Biofilm formation and dynamics in the marine cyanobacterium Prochlorococcus.Nature communications · 2026Article
- ModifiedMicroorganisms · 2026Article
- Effect of cellular nutrient economy on the evolution of genome size in phytoplankton.Science advances · 2026Article
- Phosphorus Acquisition Strategies Among Phytoplankton and Free-Living Bacterial Communities in the Baltic Proper.Environmental microbiology reports · 2026Article
- Spatiotemporal 4D Whole-cell Modeling of a Minimal Autotroph Reveals Central Carbon Metabolism Regulated Locally by Protein Megacomplexes via Post-translational ModiBications under Light Disturbance.bioRxiv : the preprint server for biology · 2026Article
- Dealing with phosphorus deficiency: contrasting strategies in marine phytoplankton and bacteria.ISME communications · 2026Article
- Phosphorus acquisition among planktonic microbial communities across a salinity gradient.ISME communications · 2026Article
- Genome Sequences of the First Phages InfectingMicroorganisms · 2025Article
- Climate-driven succession in marine microbiome biodiversity and biogeochemical function.Nature communications · 2025Article
- Gene content of seawater microbes is a strong predictor of water chemistry across the Great Barrier Reef.Microbiome · 2025Article
- Adaptive Responses of Cyanobacteria to Phosphate Limitation: A Focus on Marine Diazotrophs.Environmental microbiology · 2024Review
- A distinct, high-affinity, alkaline phosphatase facilitates occupation of P-depleted environments by marine picocyanobacteria.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Substrate specificity and ecological significance of PstS homologs in phosphorus uptake in marineMicrobiology spectrum · 2024Article
- Exploring virus-host-environment interactions in a chemotrophic-based underground estuary.Environmental microbiome · 2024Article
- Coordinated transcriptional response to environmental stress by a Synechococcus virus.The ISME journal · 2024Article
- Nitrogen uptake rates and phytoplankton composition across contrasting North Atlantic Ocean coastal regimes north and south of Cape Hatteras.Frontiers in microbiology · 2024Article
- Phosphate-related genomic islands as drivers of environmental adaptation in the streamlined marine alphaproteobacterial HIMB59.mSystems · 2023Article
- Global scale phylogeography of functional traits and microdiversity in Prochlorococcus.The ISME journal · 2023Article
- Marine picocyanobacterial PhnD1 shows specificity for various phosphorus sources but likely represents a constitutive inorganic phosphate transporter.The ISME journal · 2023Article
- Intra-population genomic diversity of the bloom-forming cyanobacterium, Aphanizomenon gracile, at low spatial scale.ISME communications · 2023Article
84 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cyanobacterium Prochlorococcus is the numerically dominant phototroph in the oligotrophic oceans. This group consists of multiple ecotypes that are physiologically and phylogenetically distinct and occur in different abundances along environmental gradients. Here we examine adaptations to phosphate (P) limitation among ecotypes. First, we used DNA microarrays to identify genes involved in the P-starvation response in two strains belonging to different ecotypes, MED4 (high-light-adapted) and MIT9313 (low-light-adapted). Most of the up-regulated genes under P starvation were unique to one strain. In MIT9313, many ribosomal genes were down-regulated, suggesting a general stress response in this strain. We also observed major differences in regulation. The P-starvation-induced genes comprise two clusters on the chromosome, the first containing the P master regulator phoB and most known P-acquisition genes and the second, absent in MIT9313, containing genes of unknown function. We examined the organization of the phoB gene cluster in 11 Prochlorococcus strains belonging to diverse ecotypes and found high variability in gene content that was not congruent with rRNA phylogeny. We hypothesize that this genome variability is related to differences in P availability in the oceans from which the strains were isolated. Analysis of a metagenomic library from the Sargasso Sea supports this hypothesis; most Prochlorococcus cells in this low-P environment contain the P-acquisition genes seen in MED4, although a number of previously undescribed gene combinations were observed.
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