Evidence map›Paper›PMID 16895945›Full record

Trial reportBMJ (Clinical research ed.)2006

Immediate computed tomography or admission for observation after mild head injury: cost comparison in randomised controlled trial.

Anders Norlund, Lars-Ake Marké, Jean-Luc af Geijerstam, Sven Oredsson, Mona Britton, OCTOPUS Study

Abstract readComparative StudyMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ (Clinical research ed.), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
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  11. Article
  12. Article
  13. Review
  14. [Mild head injury in children and adults: Diagnostic challenges in the emergency department].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2015
    Article
  15. Article
  16. Article
  17. "Sport" and "non-sport" concussions.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011
    Article
  18. The Irish 'health basket': a basket case?The European journal of health economics : HEPAC : health economics in prevention and care · 2010
    Article
  19. Outcome after complicated minor head injury.AJNR. American journal of neuroradiology · 2008
    Article
  20. Clinical management of patients with minor head injuries.International journal of health sciences · 2007
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Anders NorlundDepartment of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, 171 76 Stockholm, Sweden.
Lars-Ake Marké
Jean-Luc af Geijerstam
Sven Oredsson
Mona Britton
OCTOPUS Study

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare the costs of immediate computed tomography during triage for admission with those of observation in hospital in patients with mild head injury.

designProspective cost effectiveness analysis within a multicentre, pragmatic randomised trial.

setting39 acute hospitals in Sweden

participants2602 patients (aged > or = 6) with mild head injury.

interventionsImmediate computed tomography or admission for observation.

main outcome measuresDirect and indirect costs related to the mild head injury during the acute and three month follow-up period.

resultsOutcome after three months was similar for both strategies (non-significantly in favour of computed tomography). For the acute stage and complications, the cost was 461 euros (314 pounds sterling, 582 dollars) per patient in the computed tomography group and 677 euros (462 pounds sterling, 854 dollars) in the observation group; an average of 32% less in the computed tomography group (216 euros, 95% confidence interval -272 to -164; P < 0.001). Sensitivity analysis showed that computed tomography was the most cost effective strategy under a broad range of assumptions. After three months, total costs were 718 euros and 914 euros per patient-that is, 196 euros less in the computed tomography group (- 281 to - 114; P < 0.001). The lower cost of the computed tomography strategy at the acute stage thus remained unchanged during follow-up.

conclusionPatients with mild head injury attending an emergency department can be managed more cost effectively with computed tomography rather than admission for observation in hospital.

trial registrationISRCTN81464462.

Indexed as

AdolescentAdultAgedChildCosts and Cost AnalysisCraniocerebral TraumaFollow-Up StudiesHospitalizationHumansMiddle AgedProspective StudiesSwedenTomography, X-Ray Computed

Identifiers

PMID16895945
PMCPMC1557926

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.