Evidence map›Paper›PMID 16894341›Full record

ReviewNature reviews. Microbiology2006

Fundamental processes in the evolutionary ecology of Lyme borreliosis.

Klaus Kurtenbach, Klára Hanincová, Jean I Tsao, Gabriele Margos, Durland Fish, Nicholas H Ogden

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 225 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
225citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

225 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Surveillance forCanada communicable disease report = Releve des maladies transmissibles au Canada · 2026
    Article
  7. Molecular survey ofCurrent research in parasitology & vector-borne diseases · 2026
    Article
  8. Article
  9. The First Study ofPathogens (Basel, Switzerland) · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Pathogens (Basel, Switzerland) · 2025
    Article
  15. Article
  16. Article
  17. Multilocus Sequence Typing Unveils Two Novel Genospecies ofTransboundary and emerging diseases · 2025
    Article
  18. Article
  19. Adaptive immunity inApplied and environmental microbiology · 2024
    Article
  20. Article

165 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Klaus KurtenbachDepartment of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK. kk221@bath.ac.uk
Klára Hanincová
Jean I Tsao
Gabriele Margos
Durland Fish
Nicholas H Ogden

Funding

Wellcome Trust
6 · The paper itself

Abstract

The evolutionary ecology of many emerging infectious diseases, particularly vector-borne zoonoses, is poorly understood. Here, we aim to develop a biological, process-based framework for vector-borne zoonoses, using Borrelia burgdorferi sensu lato (s.l.), the causative agent of Lyme borreliosis in humans, as an example. We explore the fundamental biological processes that operate in this zoonosis and put forward hypotheses on how extrinsic cues and intrinsic dynamics shape B. burgdorferi s.l. populations. Additionally, we highlight possible epidemiological parallels between B. burgdorferi s.l. and other vector-borne zoonotic pathogens, including West Nile virus.

Indexed as

Biological EvolutionAnimalsArachnid VectorsBorrelia burgdorferiBorrelia burgdorferi GroupEcologyHumansIxodesLife Cycle StagesLyme DiseaseModels, BiologicalWest Nile virusZoonoses

Identifiers

PMID16894341

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.