Evidence map›Paper›PMID 16892035›Full record

ReviewNature medicine2006

Tumor metastasis: mechanistic insights and clinical challenges.

Patricia S Steeg

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02009852 (The Role of microRNA-29b in the Oral Squamous Cell Carcinoma), which is not on this map. Cited by 1,033 papers.

0numbers the graph read from it
0cells of the map it votes in
1,033citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02009852 unknown statusnot on this mapstarted 2014, after this paper: background citation

The Role of microRNA-29b in the Oral Squamous Cell Carcinoma

Typeobservational_patient_registrySponsorNational Taiwan University HospitalRan2014Enrolled100ConditionsOral Cancer
3 · Its place in the literature

Who cites it

1,033 citing papers in PubMed.

  1. Article
  2. Concomitant induction of apoptosis and suppression of epithelial-mesenchymal transition (EMT) by a Cu(II)-flavonoid complex in colorectal cancer.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
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  6. Review
  7. Article
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973 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Patricia S SteegWomen's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute Building 37, Room 1122, National Institutes of Health, Bethesda, Maryland 20892, USA. steegp@mail.nih.gov

Funding

Molecular Biology of the Metastatic PhenotypeZIASC000892 · NCI · DIVISION OF CLINICAL SCIENCES - NCI · PI STEEG, PATRICIA SCHRIVER · 2009 to 2023
$8.4M
MOLECULAR BIOLOGY OF THE METASTATIC PHENOTYPEZ01SC000892 · SC · DIVISION OF CLINICAL SCIENCES - NCI · PI STEEG, PATRICIA SCHRIVER · 1996 to 2008
$1.3M
Intramural NIH HHS
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCapillary PermeabilityGene Expression Regulation, NeoplasticHumansModels, BiologicalNeoplasm InvasivenessNeoplasm MetastasisNeoplasmsNeoplasms, ExperimentalNeoplastic Cells, CirculatingNeovascularization, Pathologic

Identifiers

PMID16892035

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.