ArticleJournal of Korean medical science2006
Primary osteosarcoma in patients older than 40 years of age.
Article in Journal of Korean medical science, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence and risk factors of distant metastasis among Chinese osteosarcoma patients: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- Prognostic factors in canine appendicular osteosarcoma - a meta-analysis.BMC veterinary research · 2012Pooled it
- Comparison of overall survival of adult and pediatric osteosarcoma patients using the national cancer database.BMC cancer · 2025Article
- Review
- Primary osteosarcoma of the sphenoid wing in a middle-aged woman with extensive intracranial extension: A case report.Journal of Taibah University Medical Sciences · 2021Article
- Prognostic factors in osteosarcoma: A study level meta-analysis and systematic review of current practice.Journal of bone oncology · 2020Article
- Primary osteosarcoma in elderly patients: A report of three cases.Oncology letters · 2019Article
- Survival analysis of elderly patients with osteosarcoma.International orthopaedics · 2019Article
- Prognosis of Primary Osteosarcoma in Elderly Patients: A Comparison between Young and Elderly Patients.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2019Article
- Periosteal pseudotumor in complex total knee arthroplasty resembling a neoplastic process.World journal of orthopedics · 2018Article
- Primary Osteosarcoma in the Elderly Revisited: Current Concepts in Diagnosis and Treatment.Current oncology reports · 2018Review
- Plain radiologic findings and chronological changes of incipient phase osteosarcoma overlooked by primary physicians.Clinics in orthopedic surgery · 2014Article
- Osteosarcoma: improvement in survival limited to high-grade patients only.Journal of cancer research and clinical oncology · 2011Article
- Relationships between plain-film radiographic patterns and clinicopathologic variables in AJCC stage II osteosarcoma.Skeletal radiology · 2008Article
- A review of clinical and molecular prognostic factors in osteosarcoma.Journal of cancer research and clinical oncology · 2008Review
- The Role of Chemotherapy in the Survival Benefits of Patients Aged Older Than 40 Years With Osteosarcoma.Technology in cancer research & treatmentArticle
- Characteristics and Prognostic Factors of Patients With Osteosarcoma Older Than 60 Years From the SEER Database.Cancer control : journal of the Moffitt Cancer CenterArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among the 665 patients who registered at our hospital, we reviewed 39 cases of high grade primary osteosarcoma in patients who were older than 40 yr of age. The aim of this study was to determine if a primary osteosarcoma in older patients has different clinical features, and a poorer prognosis than in younger patients. Two evaluations were performed. In the first, an attempt was made to determine the possible prognostic factors such as gender, location, size, alkaline phosphatase, radiological findings, chemotherapy intensity, chemotherapy-induced tumor necrosis, and surgical margin. The second evaluation involved assessment of whether there were any significant clinical differences between older patients and adolescents. According to the results, a primary osteosarcoma in older patients did not reveal any significant prognostic variables. A primary osteosarcoma in older patients showed a poorer prognosis due to relatively unusual locations, common abnormal radiological findings, and a poor response to chemotherapy. Therefore, careful attention should be paid to making an accurate diagnosis and new strategies for more effective treatment, including chemotherapy, must to be developed in order to achieve long term survival in older patients with osteosarcoma.
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