Evidence map›Paper›PMID 16891541›Full record

ArticleJournal of clinical microbiology2006

Azole resistance of Candida glabrata in a case of recurrent fungemia.

Brunella Posteraro, Mario Tumbarello, Marilena La Sorda, Teresa Spanu, Enrico Maria Trecarichi, Flavia De Bernardis, Giancarlo Scoppettuolo, Maurizio Sanguinetti, Giovanni Fadda

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 32 citations in OpenAlex.

  1. Antifungal Testing of VaginalJournal of fungi (Basel, Switzerland) · 2025
    Article
  2. OverlookedbioRxiv : the preprint server for biology · 2023
    Article
  3. InJournal of fungi (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Article
  6. Fungal Profile of Vulvovaginal Candidiasis in a Tertiary Care Hospital.Journal of clinical and diagnostic research : JCDR · 2017
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Brunella PosteraroDepartment of Microbiology, Università Cattolica del Sacro Cuore, Largo F. Vito 1, Rome 00168, Italy.
Mario Tumbarello
Marilena La Sorda
Teresa Spanu
Enrico Maria Trecarichi
Flavia De Bernardis
Giancarlo Scoppettuolo
Maurizio Sanguinetti
Giovanni Fadda
Università Cattolica del Sacro Cuore · ITIstituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of recurrent Candida glabrata fungemia that became unresponsive to fluconazole treatment. Posttreatment isolates from blood and vaginal cultures of the immunocompetent patient were azole resistant and exhibited upregulated expression of CgCDR1/CgCDR2 efflux pumps compared to the original isolates. Amphotericin B therapy eradicated the infection.

Indexed as

Drug Resistance, FungalAdultAmphotericin BAntifungal AgentsAzolesBloodCandida glabrataCandidiasisFemaleFungemiaGene Expression Regulation, FungalGenes, FungalHumansRecurrenceVaginaAmphotericin BAntifungal AgentsAzoles

Identifiers

PMID16891541
PMCPMC1594598
OpenAlexW1975475744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.