ArticleJournal of clinical microbiology2006
Strain-specific differences in two large Mycobacterium tuberculosis genotype clusters in isolates collected from homeless patients in New York City from 2001 to 2004.
Article in Journal of clinical microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Infectious Diseases Among People Experiencing Homelessness: A Systematic Review of the Literature in the United States and Canada, 2003-2022.Public health reports (Washington, D.C. : 1974)Pooled it
- Molecular and genomic typing for tuberculosis surveillance: A survey study in 26 European countries.PloS one · 2019Article
- Thiazomycin, nocathiacin and analogs show strong activity against clinical strains of drug-resistant Mycobacterium tuberculosis.The Journal of antibiotics · 2017Article
- Integration of molecular typing results into tuberculosis surveillance in Germany-A pilot study.PloS one · 2017Article
- Genomic epidemiology of Lineage 4 Mycobacterium tuberculosis subpopulations in New York City and New Jersey, 1999-2009.BMC genomics · 2016Article
- Epidemiologic Correlates of Pyrazinamide-Resistant Mycobacterium tuberculosis in New York City.Antimicrobial agents and chemotherapy · 2015Article
- Tuberculosis among homeless population from Medellín, Colombia: associated mental disorders and socio-demographic characteristics.Journal of immigrant and minority health · 2013Article
- Epidemiologic consequences of microvariation in Mycobacterium tuberculosis.The Journal of infectious diseases · 2012Article
- Active tuberculosis among homeless persons, Toronto, Ontario, Canada, 1998-2007.Emerging infectious diseases · 2011Article
- Housing insecurity and lack of public assistance are risk factors for tuberculin skin test conversion among persons who use illicit drugs in New York City.Journal of addiction medicine · 2009Article
- Latent tuberculosis and active tuberculosis disease rates among the homeless, New York, New York, USA, 1992-2006.Emerging infectious diseases · 2009Article
- Unsuspected and extensive transmission of a drug-susceptible Mycobacterium tuberculosis strain.BMC pulmonary medicine · 2009Article
- Factors associated with differences between conventional contact tracing and molecular epidemiology in study of tuberculosis transmission and analysis in the city of Barcelona, Spain.Journal of clinical microbiology · 2009Article
- Discovery of a novel Mycobacterium tuberculosis lineage that is a major cause of tuberculosis in Rio de Janeiro, Brazil.Journal of clinical microbiology · 2007Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We studied two large Mycobacterium tuberculosis genotype clusters associated with recent outbreaks in homeless persons to determine factors associated with these tuberculosis (TB) strains. Isolates from all culture-positive TB cases diagnosed from 1 January 2001 to 31 December 2004 were genotyped. Patients whose isolates had identical restriction fragment length polymorphism patterns and spoligotypes were considered clustered. Health department records were reviewed and reinterviews attempted for clustered cases. Patients with the Cs30 and BEs75 strains were compared to other genotypically clustered cases and to each other. The two largest genotype clusters among homeless persons were the Cs30 strain (n = 105) and the BEs75 strain (n = 47). Fifty-one (49%) patients with the Cs30 strain and 28 (60%) with the BEs75 strain were homeless. Compared to patients with the BEs75 strain, patients with the Cs30 strain were less likely to be respiratory acid-fast bacillus smear positive (51% versus 72%). Furthermore, patients with the BEs75 strain were more likely to be HIV infected (74% versus 42%), which suggests that most patients with this strain advanced to disease after recent infection. Cases in clusters of strains that have been circulating in the community over a long time period, such as the Cs30 strain, require additional investigation to determine whether clustering is a result of recent transmission or reactivation of remote infection.
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