ArticleThe Clinical biochemist. Reviews2006
Clinical applications of molecular biology for infectious diseases.
Article in The Clinical biochemist. Reviews, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Diagnostic value of a novel automated simultaneous amplification and testing method in pulmonary tuberculosis and extrapulmonary tuberculosis.Frontiers in microbiology · 2025Article
- Modeling COVID-19 Transmission Dynamics: A Bibliometric Review.International journal of environmental research and public health · 2022Review
- First Molecular Confirmation ofPathogens (Basel, Switzerland) · 2022Article
- A decontamination strategy for resolving SARS-CoV-2 amplicon contamination in a next-generation sequencing laboratory.Archives of virology · 2022Article
- Novel protein kinase C phosphorylated kinase inhibitor-matrine suppresses replication of hepatitis B virus via modulating the mitogen-activated protein kinase signal.Bioengineered · 2022Article
- Hepatitis B virus genotype is an independent prognostic factor of telbivudine and tenofovir treatment in hepatitis B surface antigen-positive pregnant women.Food science & nutrition · 2022Article
- Application of microbiological rapid on-site evaluation in respiratory intensive care units: a retrospective study.Annals of translational medicine · 2022Article
- Business intelligence tools to optimize the appropriateness of the diagnostic process for clinical and epidemiologic purposes in a multicenter veterinary pathology service.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021Article
- Interdisciplinary Approaches to COVID-19.Advances in experimental medicine and biology · 2021Article
- Recent updates on COVID-19: A holistic review.Heliyon · 2020Review
- Recent advances and challenges in electrochemical biosensors for emerging and re-emerging infectious diseases.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2020Review
- Dual-Readout Sandwich Immunoassay for Device-Free and Highly Sensitive Anthrax Biomarker Detection.Analytical chemistry · 2020Article
- The urgent need for integrated science to fight COVID-19 pandemic and beyond.Journal of translational medicine · 2020Review
- A nanoparticle pseudo pathogen for rapid detection and diagnosis of virus infection.Sensors international · 2020Article
- Evaluation of six TaqMan RT-rtPCR kits on two thermocyclers for the reliable detection of rabies virus RNA.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2019Article
- Polymerase Chain Reaction (PCR) as a Potential Point of Care Laboratory Test for Leprosy Diagnosis-A Systematic Review.Tropical medicine and infectious disease · 2018Review
- Rapid diagnosis of pulmonary tuberculosis and detection of drug resistance by combined simultaneous amplification testing and reverse dot blot.Journal of clinical pathology · 2018Article
- Portable device for the detection of colorimetric assays.Royal Society open science · 2017Article
- Aerobic Bacterial Community of American Cockroach Periplaneta americana,a Step toward Finding Suitable Paratransgenesis Candidates.Journal of arthropod-borne diseases · 2015Article
- Comparison of two multiplex PCR assays for the detection of respiratory viral infections.The clinical respiratory journal · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular biological methods for the detection and characterisation of microorganisms have revolutionised diagnostic microbiology and are now part of routine specimen processing. Polymerase chain reaction (PCR) techniques have led the way into this new era by allowing rapid detection of microorganisms that were previously difficult or impossible to detect by traditional microbiological methods. In addition to detection of fastidious microorganisms, more rapid detection by molecular methods is now possible for pathogens of public health importance. Molecular methods have now progressed beyond identification to detect antimicrobial resistance genes and provide public health information such as strain characterisation by genotyping. Treatment of certain microorganisms has been improved by viral resistance detection and viral load testing for the monitoring of responses to antiviral therapies. With the advent of multiplex PCR, real-time PCR and improvements in efficiency through automation, the costs of molecular methods are decreasing such that the role of molecular methods will further increase. This review will focus on the clinical utility of molecular methods performed in the clinical microbiology laboratory, illustrated with the many examples of how they have changed laboratory diagnosis and therefore the management of infectious diseases.
Identifiers
16886046PMC1390794What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.