Evidence map›Paper›PMID 16885577›Full record

ArticleTobacco control2006

Increased reach and effectiveness of a statewide tobacco quitline after the addition of access to free nicotine replacement therapy.

Lawrence C An, Barbara A Schillo, Annette M Kavanaugh, Randi B Lachter, Michael G Luxenberg, Ann H Wendling, Anne M Joseph

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Tobacco control, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00775944 (Trial Comparing Different Methods of Support With Stopping Smoking Offered Through The National Health Service), which is not on this map. Cited by 64 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 4 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00775944 phase4completednot on this mapstarted 2009, after this paper: background citation

Trial Comparing Different Methods of Support With Stopping Smoking Offered Through The National Health Service (NHS) Smoking Helpline

TypeinterventionalSponsorUniversity of NottinghamRan2009 to 2010Enrolled2,591ConditionsTobacco SmokingArmsProactive telephone support, Reactive (standard) telephone support, Offer of voucher for cost-free Nicotine Replacement Therapy
3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 134 citations in OpenAlex.

  1. Pooled it
  2. Telephone counselling for smoking cessation.The Cochrane database of systematic reviews · 2019
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  8. Randomized trial of a smartphone mobile application compared to text messaging to support smoking cessation.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2014
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  18. A mixed-methods study exploring free nicotine replacement therapy as a strategy to promote tobacco treatment equity at Cancer Center Cessation Initiative sites.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  19. Review
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lawrence C AnUniversity of Minnesota, Department of Internal Medicine, Division of General Medicine, Minneapolis, Minnesota 55455, USA. lcan@umn.edu
Barbara A Schillo
Annette M Kavanaugh
Randi B Lachter
Michael G Luxenberg
Ann H Wendling
Anne M Joseph
STS International · USMinneapolis VA Medical Center · USUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTobacco users receiving behavioural and pharmacological assistance are more likely to quit. Although telephone quitlines provide population access to counselling, few offer pharmacotherapy.

objectiveTo assess change in cessation rates and programme impact after the addition of free nicotine replacement therapy (NRT) to statewide quitline services. DESIGN, SETTING,

participantsAn observational study of cohorts of callers to the Minnesota QUITPLAN(SM) Helpline before (n = 380) and after (n = 373) the addition of access to free NRT.

interventionMailing of NRT (patch or gum) to callers enrolling in multi-session counselling.

main outcome measureThirty-day abstinence six months after programme registration.

resultsThe number of callers increased from 155 (SD 75) to 679 (180) per month pre-NRT to post-NRT (difference 524, 95% confidence interval (CI) 323 to 725). Post-NRT, the proportion of callers enrolling in multi-session counselling (23.4% v 90.1%, difference 66.6%, 95% CI 60.8% to 71.6%) and using pharmacotherapy (46.8% v 86.8%, difference 40.0%, 95% CI 31.3% to 47.9%) increased. Thirty-day abstinence at six months increased from 10.0% pre-NRT to 18.2% post-NRT (difference 8.2%, 95% CI 3.1% to 13.4%). Post-NRT the average number of new ex-smokers per month among registrants increased from 15.5 to 123.6 (difference 108.1, 95% CI 61.1 to 155.0). The cost per quit pre-NRT was 1362 dollars (SD 207 dollars). The cost per quit post-NRT was 1934 dollars (215 dollars) suggesting a possible increase in cost per quit (difference 572 dollars, 95% CI -12 dollars to 1157 dollars).

conclusionThe addition of free NRT to a state quitline is followed by increases in participation and abstinence rates resulting in an eightfold increase in programme impact. These findings support the addition of access to pharmacological therapy as part of state quitline services.

Indexed as

HotlinesAdministration, CutaneousAdultChewing GumCohort StudiesCombined Modality TherapyConfidence IntervalsCounselingFemaleHumansMaleMiddle AgedMinnesotaNicotineNicotinic AgonistsOutcome Assessment, Health CareChewing GumNicotineNicotinic Agonists

Identifiers

PMID16885577
PMCPMC2563594
OpenAlexW1965810029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.