ArticleJournal of bacteriology2006
Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B. bronchiseptica, B. pertussis, and B. parapertussis reveals extensive diversity in surface structures associated with host interaction.
Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Phage resistance of Bordetella avium due to an altered cell wall results in increased susceptibility to the polypeptide antibiotics colistin and polymyxin B.Scientific reports · 2025Article
- A comprehensive resource for Bordetella genomic epidemiology and biodiversity studies.Nature communications · 2022Article
- Development and Validation of Two Diagnostic Real-Time PCR (TaqMan) Assays for the Detection ofMicroorganisms · 2021Article
- A rare case ofClinical case reports · 2020Article
- Did new transmission cycles in anthropogenic, dense, host populations encourage the emergence and speciation of pathogenic Bordetella?PLoS pathogens · 2019Article
- Conservation of Ancient Genetic Pathways for Intracellular Persistence Among Animal Pathogenic Bordetellae.Frontiers in microbiology · 2019Article
- A Consistent and Predictable Commercial Broiler Chicken Bacterial Microbiota in Antibiotic-Free Production Displays Strong Correlations with Performance.Applied and environmental microbiology · 2018Article
- Environmental Origin of the GenusFrontiers in microbiology · 2017Article
- Acquisition and loss of virulence-associated factors during genome evolution and speciation in three clades of Bordetella species.BMC genomics · 2016Article
- Diversity of secretion systems associated with virulence characteristics of the classical bordetellae.Microbiology (Reading, England) · 2015Article
- Whole-genome sequencing reveals the effect of vaccination on the evolution of Bordetella pertussis.Scientific reports · 2015Article
- Draft Genome Sequence of Bordetella avium Nh1210, an Outbreak Strain of Lockjaw Syndrome.Genome announcements · 2015Article
- A genomic perspective on a new bacterial genus and species from the Alcaligenaceae family, Basilea psittacipulmonis.BMC genomics · 2014Article
- A polysaccharide lyase from Stenotrophomonas maltophilia with a unique, pH-regulated substrate specificity.The Journal of biological chemistry · 2014Article
- D-alanine modification of a protease-susceptible outer membrane component by the Bordetella pertussis dra locus promotes resistance to antimicrobial peptides and polymorphonuclear leukocyte-mediated killing.Journal of bacteriology · 2013Article
- Draft Genome Sequences of Bordetella hinzii and Bordetella trematum.Genome announcements · 2013Article
- Monoclonal antibodies directed against the outer membrane protein of Bordetella avium.Monoclonal antibodies in immunodiagnosis and immunotherapy · 2013Article
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- Bordetella avium antibiotic resistance, novel enrichment culture, and antigenic characterization.Veterinary microbiology · 2012Article
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Authors and funding
20 authors.
Funding
Abstract
Bordetella avium is a pathogen of poultry and is phylogenetically distinct from Bordetella bronchiseptica, Bordetella pertussis, and Bordetella parapertussis, which are other species in the Bordetella genus that infect mammals. In order to understand the evolutionary relatedness of Bordetella species and further the understanding of pathogenesis, we obtained the complete genome sequence of B. avium strain 197N, a pathogenic strain that has been extensively studied. With 3,732,255 base pairs of DNA and 3,417 predicted coding sequences, it has the smallest genome and gene complement of the sequenced bordetellae. In this study, the presence or absence of previously reported virulence factors from B. avium was confirmed, and the genetic bases for growth characteristics were elucidated. Over 1,100 genes present in B. avium but not in B. bronchiseptica were identified, and most were predicted to encode surface or secreted proteins that are likely to define an organism adapted to the avian rather than the mammalian respiratory tracts. These include genes coding for the synthesis of a polysaccharide capsule, hemagglutinins, a type I secretion system adjacent to two very large genes for secreted proteins, and unique genes for both lipopolysaccharide and fimbrial biogenesis. Three apparently complete prophages are also present. The BvgAS virulence regulatory system appears to have polymorphisms at a poly(C) tract that is involved in phase variation in other bordetellae. A number of putative iron-regulated outer membrane proteins were predicted from the sequence, and this regulation was confirmed experimentally for five of these.
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