Evidence map›Paper›PMID 16882544›Full record

ArticleEnvironmental health perspectives2006

Effect of prenatal exposure to polychlorinated biphenyls on incidence of acute respiratory infections in preschool Inuit children.

Frédéric Dallaire, Eric Dewailly, Carole Vézina, Gina Muckle, Jean-Philippe Weber, Suzanne Bruneau, Pierre Ayotte

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Time Trend of Persistent Organic Pollutants and Metals in Greenlandic Inuit during 1994-2015.International journal of environmental research and public health · 2021
    Article
  10. Article
  11. Early life exposures shape the CD4Scientific reports · 2019
    Article
  12. Article
  13. Temporal trends of contaminants in Arctic human populations.Environmental science and pollution research international · 2018
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. A veterinary perspective on One Health in the Arctic.Acta veterinaria Scandinavica · 2017
    Review
  19. Relationship between e-waste recycling and human health risk in India: a critical review.Environmental science and pollution research international · 2016
    Article
  20. Exposure toBioMed research international · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Frédéric DallairePublic Health Research Unit, Laval University Medical Center-Centre Hospitalier Universitaire de Québec, Québec City, Québec, Canada.
Eric Dewailly
Carole Vézina
Gina Muckle
Jean-Philippe Weber
Suzanne Bruneau
Pierre Ayotte
Centre hospitalier universitaire de Québec · CAInstitut National de Santé Publique du Québec · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe set out to assess whether environmental prenatal exposure to polychlorinated biphenyls (PCBs) is associated with incidence of acute respiratory infections in preschool Inuit children. STUDY

designWe reviewed the medical charts of 343 children from 0 to 5 years of age and evaluated the associations between PCB-153 concentration in umbilical cord plasma and the incidence rates of acute otitis media (AOM) and of upper and lower respiratory tract infections (URTIs and LRTIs, respectively).

resultsThe incidence rates of AOM and LRTIs were positively associated with prenatal exposure to PCBs. Compared with children in the first quartile of exposure (least exposed), children in fourth quartile (most exposed) had rate ratios of 1.25 (p<0.001) and 1.40 (p<0.001) for AOM and LRTIs, respectively. There was no association between prenatal PCB exposure and incidence rate of URTIs or hospitalization.

conclusionPrenatal exposure to PCBs could be responsible for a significant portion of respiratory infections in children of this population.

Indexed as

Acute DiseaseAge FactorsChildChild, PreschoolCohort StudiesEnvironmental PollutantsFemaleFetal BloodHumansInfantInuitLipidsMaleMetals, HeavyNunavutOtitis MediaEnvironmental PollutantsLipidsMetals, HeavyPolychlorinated Biphenyls

Identifiers

PMID16882544
PMCPMC1552004
OpenAlexW2093358132

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.