ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2006
Milestones in the natural course of onset of cigarette use among adolescents.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 4 of them syntheses that pooled it.
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Who cites it
77 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Association Between Initial Use of e-Cigarettes and Subsequent Cigarette Smoking Among Adolescents and Young Adults: A Systematic Review and Meta-analysis.JAMA pediatrics · 2017Pooled it
- Stimulant treatment of ADHD and cigarette smoking: a meta-analysis.Pediatrics · 2014Pooled it
- Members, isolates, and liaisons: meta-analysis of adolescents' network positions and their smoking behavior.Substance use & misuse · 2013Pooled it
- Smoking cessation attempts among adolescent smokers: a systematic review of prevalence studies.Tobacco control · 2007Pooled it
- Acute phenylalanine/tyrosine depletion reduces motivation to smoke cigarettes across stages of addiction.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2011Trial
- Effectiveness of a school nurse-delivered smoking-cessation intervention for adolescents.Pediatrics · 2011Trial
- [Nicotine consumption in childhood and adolescence-fundamentals and considerations for handling the topic in child and adolescent psychiatric settings].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2026Article
- Unveiling binge drinking trends and triggers among army personnel: a cross sectional study.Substance abuse treatment, prevention, and policy · 2025Article
- Longitudinal patterns of e-cigarette use initiation and progression to frequent vaping from mid-to-late adolescence to young adulthood.Addiction (Abingdon, England) · 2025Article
- Behavioral Precursors of Nicotine Product Use Trajectories Among Youth.American journal of preventive medicine · 2024Article
- Article
- Dopamine D1-like receptor activation decreases nicotine intake in rats with short or long access to nicotine.Addiction biology · 2023Article
- Development of Dependence in Smokers and Rodents With Voluntary Nicotine Intake: Similarities and Differences.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023Review
- Reinforcement enhancement by nicotine: A novel abuse-liability assessment of e-cigarettes in young adults.Experimental and clinical psychopharmacology · 2022Article
- Initiation or cessation: what keeps the prevalence of smoking higher in Quebec than in the rest of Canada?Health promotion and chronic disease prevention in Canada : research, policy and practice · 2021Article
- The reinforcement threshold and elasticity of demand for nicotine in an adolescent rat model of depression.Drug and alcohol dependence · 2021Article
- Predictors of nicotine dependence among adolescent waterpipe and cigarette smokers: A 6-year longitudinal analysis.Drug and alcohol dependence · 2020Article
- Parental Awareness of Youth Tobacco Use and the Role of Household Tobacco Rules in Use Prevention.Pediatrics · 2020Article
- Is Smoking Cessation in Young Adults Associated With Tobacco Retailer Availability in Their Activity Space?Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020Article
- Childhood/Adolescent Smoking and Adult Smoking and Cessation: The International Childhood Cardiovascular Cohort (i3C) Consortium.Journal of the American Heart Association · 2020Article
17 more citing papers are in PubMed but not listed here.
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5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe natural course of onset of cigarette use has been conceptualized as progressing sequentially through 5 stages (preparation, trying, irregular use, regular use, nicotine-dependent smoking). However, recent studies suggest that symptoms of nicotine dependence can occur early in the onset process, raising questions about the validity of this model. The objective of our study was to describe the sequence and timing of 12 milestones (6 related to cigarette use and 6 to symptoms of nicotine dependence) during onset of cigarette use.
methodsGrade 7 students in 10 secondary schools in Montréal (n = 1293) were followed prospectively every 3-4 months for 5 years. Using Kaplan-Meier analysis, we computed the number of months after first puff at which the cumulative probability of attaining each milestone was 25%, among 311 participants who initiated cigarette use during follow-up.
resultsInhalation rapidly followed first puff. The cumulative probability of inhalation was 25% at 1.5 months (95% confidence interval [CI] 1.5-2.5). The cumulative probability (and 95% CI) was 2.5 months (1.5-2.5) for mental addiction, 2.5 (1.0-3.0) for smoking a whole cigarette, 4.5 (2.5-8.8) for cravings, 5.4 (3.8-9.7) for physical addiction, 8.8 (7.0-11.9) for monthly smoking, 11.0 (6.4-16.8) for withdrawal symptoms, 13.0 (10.3-20.5) for tolerance, 19.4 (14.5-31.7) for weekly smoking, 19.5 (14.0-23.9) for lifetime total of 100 cigarettes, 23.1 (19.7-37.6) for daily smoking and 40.6 (35.1-56.0) for conversion to tobacco dependence.
interpretationSymptoms of nicotine dependence develop soon after first puff and can precede monthly, weekly and daily smoking. Cessation interventions that manage dependence symptoms may be needed soon after first puff.
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