Evidence map›Paper›PMID 16880225›Full record

ArticleArchives of disease in childhood2007

Reference chart for relative weight change to detect hypernatraemic dehydration.

Paula van Dommelen, Jacobus P van Wouwe, Jacqueline M Breuning-Boers, Stef van Buuren, Paul H Verkerk

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in Archives of disease in childhood, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Early diagnosis of neonatal-onset cyclic vomiting syndrome.Nagoya journal of medical science · 2023
    Article
  8. Observational
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Designing the new UK-WHO growth charts to enhance assessment of growth around birth.Archives of disease in childhood. Fetal and neonatal edition · 2012
    Article
  16. Article
  17. First-day newborn weight loss predicts in-hospital weight nadir for breastfeeding infants.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2010
    Article
  18. Article
  19. Breast feeding.BMJ (Clinical research ed.) · 2008
    Review
  20. Avoiding hypernatraemic dehydration in healthy term infants.Archives of disease in childhood · 2007
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Paula van DommelenTNO Quality of Life, Leiden, The Netherlands. P.vanDommelen@pg.tno.nl
Jacobus P van Wouwe
Jacqueline M Breuning-Boers
Stef van Buuren
Paul H Verkerk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe validity of the rule of thumb that infants may have a weight loss of 10% in the first days after birth is unknown. We assessed the validity of this and other rules to detect breast-fed infants with hypernatraemic dehydration.

designA reference chart for relative weight change was constructed by the LMS method. The reference group was obtained by a retrospective cohort study.

participants1544 healthy, exclusively breast-fed infants with 3075 weight measurements born in the Netherlands and 83 cases of breast-fed infants with hypernatraemic dehydration obtained from literature.

resultsThe rule of thumb had a sensitivity of 90.4%, a specificity of 98.3% and a positive predictive value of 3.7%. Referring infants if their weight change is below -2.5 SDS (0.6th centile) in the reference chart in the first week of life and using the rule of thumb in the second week had a sensitivity of 85.5%, a specificity of 99.4% and a positive predictive value of 9.2%.

conclusionsThe rule of thumb is likely to produce too many false positive results, assuming that for screening purposes the specificity needs to be high. A chart for relative weight change can be helpful to detect infants with hypernatraemic dehydration.

Indexed as

Weight LossBreast FeedingDehydrationEpidemiologic MethodsEvidence-Based MedicineFemaleHumansHypernatremiaInfant CareInfant, NewbornMaleNetherlandsReference ValuesReferral and Consultation

Identifiers

PMID16880225
PMCPMC2066175

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.