Evidence map›Paper›PMID 16877474›Full record

ArticleArchives of disease in childhood2006

Rapidly increasing prevalence of eosinophilic oesophagitis in Western Australia.

S Cherian, N M Smith, D A Forbes

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Archives of disease in childhood, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03290482 (Natural History of Eosinophilic Esophagitis), which is not on this map. Cited by 63 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 2 pooled it
16.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03290482 completednot on this mapstarted 2017, after this paper: background citation

Natural History of Eosinophilic Esophagitis: A Longitudinal Follow-up Over 10 Years

TypeobservationalSponsorMayo ClinicRan2017 to 2020Enrolled65ConditionsEosinophilic EsophagitisArmsBarium Esophagram, EsophaCap, Physical Examination and Questionnaires
3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 2 syntheses or guidelines pooled it, 231 citations in OpenAlex.

  1. Natural history of eosinophilic esophagitis: a systematic review of epidemiology and disease course.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2018
    Pooled it
  2. The prevalence and diagnostic utility of endoscopic features of eosinophilic esophagitis: a meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2012
    Pooled it
  3. Trial
  4. Review
  5. Review
  6. Eosinophilic esophagitis in children: A cross-sectional study from a tertiary care center.JGH open : an open access journal of gastroenterology and hepatology · 2024
    Article
  7. Increasing incidence of eosinophilic esophagitis in Sweden: a nationwide population study.Esophagus : official journal of the Japan Esophageal Society · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Classification of eosinophilic disorders of the small and large intestine.Virchows Archiv : an international journal of pathology · 2018
    Article
  12. Review
  13. Review
  14. IgE-associated food allergy alters the presentation of paediatric eosinophilic esophagitis.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2016
    Article
  15. Article
  16. Eosinophilic Esophagitis: A Comprehensive Review.Clinical reviews in allergy & immunology · 2016
    Review
  17. An Overview of the Diagnosis and Management of Eosinophilic Esophagitis.Clinical and translational gastroenterology · 2016
    Review
  18. Eosinophilic esophagitis: New insights in pathogenesis and therapy.World journal of gastrointestinal pharmacology and therapeutics · 2016
    Review
  19. The Immunologic Mechanisms of Eosinophilic Esophagitis.Current allergy and asthma reports · 2016
    Review
  20. Wheat allergy: diagnosis and management.Journal of asthma and allergy · 2016
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

S CherianDepartment of Histopathology, PathWest Laboratory Medicine (KEMH/PMH), Perth, Australia. Sarah.Cherian@health.wa.gov.au
N M Smith
D A Forbes
Pathwest Laboratory Medicine · AUUniversity of Western Australia · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo assess the prevalence of eosinophilic oesophagitis in a tertiary paediatric gastroenterology clinic population.

methodsA retrospective audit of Western Australian children investigated for oesophageal disease by paediatric gastroenterologists in the years 1995, 1999 and 2004. Macroscopic appearance of the oesophagus at endoscopy, original histological findings and diagnosis were recorded for each child. Biopsy specimens were blindly re-evaluated, with re-coded histological diagnoses compared with original reports. Age, sex and socioeconomic status were identified for each child.

resultsThe prevalence of eosinophilic oesophagitis in Western Australia increased over the decade 1995-2004, rising from 0.05 to 0.89 per 10 000 children, with a concomitant increase in the severity of oesophagitis as determined by inflammatory cell numbers and associated features of inflammation. Children diagnosed with eosinophilic oesophagitis had a median age of 78.9 months (6.58 years), with no associated predisposition by sex or socioeconomic status trend. Almost one third of cases were macroscopically normal at endoscopy. All children with an original diagnosis of eosinophilic oesophagitis had > or =40 eosinophils per high-power field.

conclusionOver the decade 1995-2004, a true increase was seen in the prevalence of eosinophilic oesophagitis, not accounted for by diagnostic shift. Histological samples should be taken at endoscopy to confirm or exclude the diagnosis of eosinophilic oesophagitis.

Indexed as

BiopsyChildChild, PreschoolEosinophiliaEsophagitisFemaleHumansInfantMalePrevalenceRetrospective StudiesWestern Australia

Identifiers

PMID16877474
PMCPMC2083004
OpenAlexW2139323666

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.