ArticleCurrent microbiology2006
Isolation, characterization, and transcriptional analysis of the chitinase chi2 Gene (DQ011663) from the biocontrol fungus Metarhizium anisopliae var. anisopliae.
Article in Current microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 44 citations in OpenAlex.
- Genome sequencing and functional annotation of Metarhizium anisopliae TNAU-MA-GDU: Insights into virulence mechanisms against Spodoptera frugiperda.Molecular biology reports · 2026Article
- The chitinolytic enzymes from the entomopathogenic fungusFrontiers in fungal biology · 2026Review
- Expression profiles and characterization of microRNAs responding to chitin in Arthrobotrys oligospora.Archives of microbiology · 2024Article
- Genome-Wide Identification and Analysis of Chitinase GH18 Gene Family inFrontiers in microbiology · 2020Article
- Genome sequence and comparative analysis of clavicipitaceous insect-pathogenic fungus Aschersonia badia with Metarhizium spp.BMC genomics · 2016Article
- Secretome Analysis of Metarhizium anisopliae Under Submerged Conditions Using Bombyx mori Chrysalis to Induce Expression of Virulence-Related Proteins.Current microbiology · 2016Article
- Genome sequence, comparative analysis, and evolutionary insights into chitinases of entomopathogenic fungus Hirsutella thompsonii.Genome biology and evolution · 2015Article
- Article
- Use of Metarhizium anisopliae chitinase genes for genotyping and virulence characterization.BioMed research international · 2013Article
- Fungal chitinases: diversity, mechanistic properties and biotechnological potential.Applied microbiology and biotechnology · 2012Review
- Endochitinase CHI2 of the biocontrol fungus Metarhizium anisopliae affects its virulence toward the cotton stainer bug Dysdercus peruvianus.Current genetics · 2009Article
- Purification and characterization of chitinases from Paecilomyces variotii DG-3 parasitizing on Meloidogyne incognita eggs.Journal of industrial microbiology & biotechnology · 2009Article
- Cloning and expression analysis of the chitinase gene Ifu-chit2 from Isaria fumosorosea.Genetics and molecular biologyArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metarhizium anisopliae infects arthropods via a combination of specialized structures and cuticle degradation. Hydrolytic enzymes are accepted as key factors for the host penetration step and include chitinases. The characterization of the chi2 chitinase gene from M. anisopliae var. anisopliae is reported. The chi2 gene is interrupted by two short introns and is 1,542-bp long, coding a predicted protein of 419 amino acids with a stretch of 19 amino acid residues displaying characteristics of signal peptide. The predicted chitinase molecular mass is 44 kDa with a mature protein of 42 kDa and a theoretical pI of 4.8. The comparison of the CHI2 predicted protein to fungal orthologues revealed similarity to the glycohydrolase family 18 and a phylogenetic analysis was conducted. The chi2 gene is up-regulated by chitin as a carbon source and in conditions of fungus autolysis, and is down-regulated by glucose. This regulation is consistent with the presence of putative CreA/Crel/Crr1 carbon catabolic repressor binding domains on the regulatory sequence.
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