ArticleSchizophrenia bulletin2006
Predictors of psychosis remission in psychotic disorders that co-occur with substance use.
Article in Schizophrenia bulletin, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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16 citing papers in PubMed, 1 synthesis or guideline pooled it.
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- Predicting functional remission in patients with schizophrenia: a cross-sectional study of symptomatic remission, psychosocial remission, functioning, and clinical outcome.Neuropsychiatric disease and treatment · 2015Article
- The neuroanatomical correlates of cognitive insight in schizophrenia.Social cognitive and affective neuroscience · 2013Article
- Personalized risk assessment of drug-related harm is associated with health outcomes.PloS one · 2013Article
- Empirically Based Psychosocial Therapies for Schizophrenia: The Disconnection between Science and Practice.Schizophrenia research and treatment · 2013Article
- Remission in schizophrenia: validity, frequency, predictors, and patients' perspective 5 years later.Dialogues in clinical neuroscience · 2010Review
- Factors associated with remission from alcohol dependence in an American Indian community group.The American journal of psychiatry · 2008Article
- Mental health laws that require dangerousness for involuntary admission may delay the initial treatment of schizophrenia.Social psychiatry and psychiatric epidemiology · 2008Article
- Evidence for a relationship between the duration of untreated psychosis and the proportion of psychotic homicides prior to treatment.Social psychiatry and psychiatric epidemiology · 2008Review
- Developing and testing adaptive treatment strategies using substance-induced psychosis as an example.Psychopharmacology bulletin · 2008Article
- Encephalopathy or Psychosis?Innovations in clinical neuroscienceArticle
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7 authors.
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Abstract
objectiveTo examine rates and predictors of psychosis remission at 1-year follow-up for emergency admissions diagnosed with primary psychotic disorders and substance-induced psychoses.
methodA total of 319 patients with comorbid psychosis and substance use, representing 83% of the original referred sample, were rediagnosed at 1 year postintake employing a research diagnostic assessment. Remission of psychosis was defined as the absence of positive and negative symptoms for at least 6 months. Likelihood ratio chi-square tests and multivariate logistic regression were the main means of analysis.
resultsOf those with a baseline diagnosis of primary psychotic disorder, 50% were in remission at 1 year postintake, while of those with a baseline diagnosis of substance-induced psychosis, 77% were in remission at this time point. Lower Positive and Negative Syndrome Scale (PANSS) symptom levels at baseline, better premorbid functioning, greater insight into psychosis, and a shorter duration of untreated psychosis predicted remission at 1 year in both diagnostic groups. No interaction effects of baseline predictors and diagnosis type were observed. A stepwise multivariate logistic regression holding baseline diagnosis constant revealed the duration of untreated psychosis (odds ratio [OR] = 0.97; 95% confidence interval [CI] = 0.95, 0.997), total PANSS score (OR = 0.98; 95% CI = 0.97, 0.987), Premorbid Adjustment Scale score (OR = 0.13; 95% CI = 0.02, 0.88), and Scale to Assess Unawareness of Mental Disorders unawareness score (OR = 0.84; 95% CI = 0.71, 0.993) as key predictors of psychosis remission.
conclusionsThe association of better premorbid adjustment, a shorter duration of untreated psychosis, better insight into psychotic symptoms, and lower severity of psychotic symptoms with improved clinical outcome, reported previously in studies of schizophrenia, generalizes to psychosis remission in psychotic disorders that are substance induced.
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