Evidence map›Paper›PMID 16870779›Full record

ArticleAntimicrobial agents and chemotherapy2006

Killing kinetics of caspofungin, micafungin, and amphotericin B against Candida guilliermondii.

Emilia Cantón, Javier Pemán, Macrina Sastre, Mónica Romero, Ana Espinel-Ingroff

Abstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. International journal of molecular sciences · 2025
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Fungal echinocandin resistance.F1000 biology reports · 2010
    Article
  9. Article
  10. Article
  11. Fungal echinocandin resistance.Fungal genetics and biology : FG & B · 2010
    Article
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Emilia CantónUnidad de Microbiología Experimental-Centro de Investigación, Hospital Universitario La Fe, 46009 Valencia, Spain. canton_emi@gva.es
Javier Pemán
Macrina Sastre
Mónica Romero
Ana Espinel-Ingroff

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amphotericin B (AMB), micafungin, and caspofungin MICs, minimal fungicidal concentrations, and time-killing curves were determined in the presence and absence of 10% inactivated serum. AMB was the only agent with consistent killing activity (time required to achieve 99.9% of growth reduction was 2.1 to 3.2 h). The presence of serum enhanced caspofungin activity but lowered those of micafungin and AMB.

Indexed as

Amphotericin BAntifungal AgentsCandidaCandidiasisCaspofunginEchinocandinsKineticsLipopeptidesLipoproteinsMicafunginMicrobial Sensitivity TestsPeptides, CyclicAmphotericin BAntifungal AgentsCaspofunginEchinocandinsLipopeptidesLipoproteinsMicafunginPeptides, Cyclic

Identifiers

PMID16870779
PMCPMC1538680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.