ArticleBritish journal of cancer2006
Risk of breast, ovary, and uterine corpus cancers among 85,268 women with AIDS.
Article in British journal of cancer, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
45 citing papers in PubMed, 3 syntheses or guidelines pooled it, 87 citations in OpenAlex.
- Cancer disparities in people with HIV: A systematic review of screening for non-AIDS-defining malignancies.Cancer · 2019Pooled it
- A meta-analysis of the incidence of non-AIDS cancers in HIV-infected individuals.Journal of acquired immune deficiency syndromes (1999) · 2009Pooled it
- HIV and prostate cancer: a systematic review of the literature.Prostate cancer and prostatic diseases · 2009Pooled it
- Epidemiological and Clinical Characteristics of Women Living with HIV in Korea.Infection & chemotherapy · 2024Article
- Navigating the Nexus: HIV and Breast Cancer-A Critical Review.International journal of molecular sciences · 2024Review
- Incidence and mortality of non-AIDS-defining cancers among people living with HIV: A systematic review and meta-analysis.EClinicalMedicine · 2022Article
- The Association Between HIV Status, Estradiol, and Sex Hormone Binding Globulin Among Premenopausal Women in the Women's Interagency HIV Study.Journal of women's health (2002) · 2022Article
- Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of breast cancer.Journal for immunotherapy of cancer · 2021Article
- The effect of non-AIDS-defining cancers on people living with HIV.The Lancet. Oncology · 2021Review
- Does HIV undermine breast cancer outcomes in women?AIDS (London, England) · 2021Article
- Cancer Incidence and Cancer Screening Practices Among a Cohort of Persons Receiving HIV Care in Washington, DC.Journal of community health · 2021Article
- Association between HIV infection and outcomes of care among medicare enrollees with breast cancer.EClinicalMedicine · 2019Article
- Breast cancer, human immunodeficiency virus and highly active antiretroviral treatment; implications for a high-rate seropositive region.Oncology reviews · 2019Article
- Risk of Breast, Prostate, and Colorectal Cancer Diagnoses Among HIV-Infected Individuals in the United States.Journal of the National Cancer Institute · 2018Article
- Gynecologic cancer in HIV-infected women: treatment and outcomes in a multi-institutional cohort.AIDS (London, England) · 2018Article
- Cancer screening in women living with HIV infection.Women's health (London, England) · 2017Article
- Deaths Due to Screenable Cancers Among People Living With HIV Infection, Florida, 2000-2014.American journal of preventive medicine · 2017Article
- South African Breast Cancer and HIV Outcomes Study: Methods and Baseline Assessment.Journal of global oncology · 2017Article
- Malignancies in women with HIV infection.Current opinion in HIV and AIDS · 2017Review
- HIV-1 matrix protein p17 and its variants promote human triple negative breast cancer cell aggressiveness.Infectious agents and cancer · 2017Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
By linking HIV/AIDS and cancer surveillance data in 12 US regions, breast and reproductive cancer risks with AIDS were compared to those in the general population. Trends in standardized incidence ratios (SIRs) were assessed by CD4 count, AIDS-relative time, and calendar time. Standardized incidence ratios were indirectly adjusted for cancer risk factors using data from AIDS cohort participants and the general population. With AIDS, 313 women developed breast cancer (SIR 0.69, 95% confidence interval (CI) 0.62-0.77), 42 developed ovary cancer (SIR 1.05, 95% CI, 0.75-1.42), and 31 developed uterine corpus cancer (SIR 0.57, 95% CI, 0.39-0.81). Uterine cancer risk was reduced significantly after age 50 (SIR 0.33). Breast cancer risk was reduced significantly both before (SIR 0.71) and after (SIR 0.66) age 50, and was lower for local or regional (SIR 0.54) than distant (SIR 0.89) disease. Breast cancer risk varied little by CD4 count (Ptrend=0.47) or AIDS-relative time (Ptrend=0.14) or after adjustment for established cancer risk factors. However, it increased significantly between 1980 and 2002 (Ptrend=0.003), approaching the risk of the general population. We conclude that the cancer deficit reflected direct or indirect effects of HIV/AIDS and that anti-HIV therapy reduced these effects.
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