ArticleGenetics2006
Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries).
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 79 citations in OpenAlex.
- Assessment of a Reduced SNP Panel Targeting Prolificacy and Coat Color Genes in Brazilian Sheep Breeds.Animals : an open access journal from MDPI · 2026Article
- Screening of molecular markers associated with hornless traits in Qira black sheep.BMC genomics · 2025Article
- Genome-based analysis of the genetic pattern of black sheep in Qira sheep.BMC genomics · 2025Article
- Construction of a high-density genetic map and QTL localization of body weight and wool production related traits in Alpine Merino sheep based on WGR.BMC genomics · 2024Article
- Genome-wide association study for polledness, horn shape, and wool traits in Original Valachian sheep.Archives animal breeding · 2024Article
- Identification of Critical Genes for Ovine Horn Development Based on Transcriptome during the Embryonic Period.Biology · 2023Article
- Genetics of the phenotypic evolution in sheep: a molecular look at diversity-driving genes.Genetics, selection, evolution : GSE · 2022Review
- Estimation of linkage disequilibrium and effective population size in New Zealand sheep using three different methods to create genetic maps.BMC genetics · 2017Article
- The 1.78-kb insertion in the 3'-untranslated region of RXFP2 does not segregate with horn status in sheep breeds with variable horn status.Genetics, selection, evolution : GSE · 2016Article
- Genome-wide linkage disequilibrium and genetic diversity in five populations of Australian domestic sheep.Genetics, selection, evolution : GSE · 2015Article
- A 1.8-kb insertion in the 3'-UTR of RXFP2 is associated with polledness in sheep.Animal genetics · 2015Article
- Towards the identification of the loci of adaptive evolution.Methods in ecology and evolution · 2015Review
- Article
- Selection methods for resistance to and tolerance of helminths in livestock.Parasite (Paris, France) · 2014Review
- Exploring the abomasal lymph node transcriptome for genes associated with resistance to the sheep nematode Teladorsagia circumcincta.Veterinary research · 2013Article
- A quantitative trait locus analysis of personality in wild bighorn sheep.Ecology and evolution · 2013Article
- Mutations in MC1R gene determine black coat color phenotype in Chinese sheep.TheScientificWorldJournal · 2013Article
- Article
- Genetic linkage map of a wild genome: genomic structure, recombination and sexual dimorphism in bighorn sheep.BMC genomics · 2010Article
- Convergence in pigmentation at multiple levels: mutations, genes and function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2010Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
An understanding of the determinants of trait variation and the selective forces acting on it in natural populations would give insights into the process of evolution. The combination of long-term studies of individuals living in the wild and better genomic resources for nonmodel organisms makes achieving this goal feasible. This article reports the development of a complete linkage map in a pedigree of free-living Soay sheep on St. Kilda and its application to mapping the loci responsible for three morphological polymorphisms for which the maintenance of variation demands explanation. The map was derived from 251 microsatellite and four allozyme markers and covers 3350 cM (approximately 90% of the sheep genome) at approximately 15-cM intervals. Marker order was consistent with the published sheep map with the exception of one region on chromosome 1 and one on chromosome 12. Coat color maps to chromosome 2 where a strong candidate gene, tyrosinase-related protein 1 (TYRP1), has also been mapped. Coat pattern maps to chromosome 13, close to the candidate locus Agouti. Horn type maps to chromosome 10, a location similar to that previously identified in domestic sheep. These findings represent an advance in the dissection of the genetic diversity in the wild and provide the foundation for QTL analyses in the study population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.