ArticlePsychological science2006
Drug-induced amnesia hurts recognition, but only for memories that can be unitized.
Article in Psychological science, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Decreased Cerebral Blood Flow in Mesial Thalamus and Precuneus/PCC during Midazolam Induced Sedation Assessed with ASL.Neuroinformatics · 2018Trial
- Disruption of cortical integration during midazolam-induced light sedation.Human brain mapping · 2015Trial
- Using arterial spin labeling perfusion MRI to explore how midazolam produces anterograde amnesia.Neuroscience letters · 2012Trial
- Differential effects of scopolamine and lorazepam on working memory maintenance versus manipulation processes.Cognitive, affective & behavioral neuroscience · 2007Trial
- Retrograde facilitation under midazolam: the role of general and specific interference.Psychonomic bulletin & review · 2007Trial
- Midazolam does not inhibit association formation, just its storage and strengthening.Psychopharmacology · 2006Trial
- Dose effects of triazolam on brain activity during episodic memory encoding: a PET study.Psychopharmacology · 2006Trial
- An item's status in semantic memory determines how it is recognized: Dissociable patterns of brain activity observed for famous and unfamiliar faces.Neuropsychologia · 2018Article
- Why it's easier to remember seeing a face we already know than one we don't: preexisting memory representations facilitate memory formation.Psychological science · 2013Article
- Opposing patterns of neural priming in same-exemplar vs. different-exemplar repetition predict subsequent memory.NeuroImage · 2011Article
- Memory systems do not divide on consciousness: Reinterpreting memory in terms of activation and binding.Psychological bulletin · 2009Review
- Characterizing the ERP Old-New effect in a short-term memory task.Psychophysiology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Midazolam is a drug that creates temporary anterograde amnesia. In a within-subjects, double-blind experiment, participants studied a list of stimuli after receiving an injection of midazolam in one session and after receiving saline in another session. The lists consisted of three types of stimuli: words, photographs, and abstract pictures. Recognition memory was tested at the end of each session. Memory was reliably poorer in the midazolam condition than the saline condition, but this amnesic effect was significantly smaller for pictorial stimuli than for words and almost nonexistent for abstract pictures. We argue that the less familiar the stimulus, the less likely it is to be associated with an experimental context. These data bolster our claim that unitization increases the chances of episodic binding and that drug-induced amnesia prevents episodic binding regardless of unitization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.