Trial reportWorld journal of gastroenterology2006
Assessment of liver fibrosis by a noninvasive method of transient elastography and biochemical markers.
Trial report in World journal of gastroenterology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Influence of lecithin cholesterol acyltransferase alteration during different pathophysiologic conditions: A 45 years bibliometrics analysis.Frontiers in pharmacology · 2022Article
- Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP-305, a novel farnesoid X receptor agonist.Hepatology communications · 2018Article
- Article
- Transient Elastography-Based Liver Profiles in a Hospital-Based Pediatric Population in Japan.PloS one · 2015Article
- Persistent hepatitis C virus infections and hepatopathological manifestations in immune-competent humanized mice.Cell research · 2014Article
- Preoperative liver function assessments to estimate the prognosis and safety of liver resections.Surgery today · 2014Review
- The relationship between transient elastography and histological collagen proportionate area for assessing fibrosis in chronic viral hepatitis.Journal of gastroenterology · 2013Article
- Discrimination of individuals in a general population at high-risk for alcoholic and non-alcoholic fatty liver disease based on liver stiffness: a cross section study.BMC gastroenterology · 2011Article
- Assessment of noninvasive liver stiffness in inactive HBsAg carriers by transient elastography: Fibroscan in inactive HBsAg carriers.Hepatitis monthly · 2011Article
- Shear wave velocity is a useful marker for managing nonalcoholic steatohepatitis.World journal of gastroenterology · 2010Article
- Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2009Article
- Correlation of Laparoscopic Liver Biopsy to Elasticity Measurements (FibroScan) in Patients With Chronic Liver Disease.Gastroenterology & hepatology · 2008Article
- Transient elastography for the assessment of chronic liver disease: ready for the clinic?World journal of gastroenterology · 2007Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo assess the correlation between the fibrotic area (FA) as calculated by a digital image analysis (DIA), and to compare the diagnostic accuracy of FibroScan to the other existing Liver fibrosis (LF) markers using the receiver operating curve analysis.
methodsWe recruited 30 patients who underwent a liver resection for three different etiologies including normal liver, hepatitis B, and hepatitis C. Liver stiffness was measured by using a FibroScan. The FA was then calculated by DIA to evaluate LF in order to avoid any sampling bias.
resultsThe FA negatively correlated with Prothrom-bin time (PT), platelet count, lecithin-cholesterol acyltransferase (LCAT), and pre-albumin (ALB). On the other hand, the findings of FibroScan correlated with similar markers. The FA positively correlated with FibroScan, serum hyaluronate level, and type IV collagen level, and aspartate transaminase to platelet ratio index (APRI). The area under the receiver operating curve for FibroScan was higher than that for the other markers, even though the statistical significance was minimal.
conclusionOur findings suggest that FibroScan can initially be used to assess LF as an alternative to a liver biopsy (LB) and serum diagnosis, because it is a safe method with comparable diagnostic accuracy regarding the existing LF markers.
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