Evidence map›Paper›PMID 16865212›Full record

ArticleSingapore medical journal2006

Association of Helicobacter pylori infection with cardiac syndrome X.

R Eskandarian, M Malek, S H Mousavi, M Babaei

Abstract read
PubMed
In one paragraph

Article in Singapore medical journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Frontiers in cardiovascular medicine · 2022
    Pooled it
  2. Definitions and incidence of cardiac syndrome X: review and analysis of clinical data.Clinical research in cardiology : official journal of the German Cardiac Society · 2010
    Pooled it
  3. Association ofMedical journal of the Islamic Republic of Iran · 2018
    Article
  4. Article
  5. Article
  6. Lipid Profile in Cardiac Syndrome X: Association with Helicobacter pylori.Journal of clinical and diagnostic research : JCDR · 2016
    Article
  7. Review
  8. Helicobacter pylori infection and the risk of acute coronary syndrome: a nationwide retrospective cohort study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

R EskandarianInternal Medicine Research Centre, Fatemieh Hospital, Semnan University of Medical Sciences, Semnan, Iran. malekmoj@yahoo.com
M Malek
S H Mousavi
M Babaei
Semnan University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCardiac syndrome X (CSX) includes chest pain, positive exercise stress test and/or radionuclide test for ischaemia and normal coronary angiography. There is no obvious aetiology for this syndrome. Some mechanisms such as endothelial dysfunction and oestrogen deficiency have been invoked. In this study, we surveyed the association of Helicobacter pylori (HP) infection with cardiac syndrome X.

methodsHP infection was detected by urea breath test (UBT) in patients with cardiac syndrome X, and compared with a sex- and age-matched control group. Patients with dyspepsia and coronary spasm were excluded. Statistical analysis was carried out using chi-square test.

results40 patients (29 females and 11 males) with cardiac syndrome X aged between 30 and 65 years (mean 45.51 +/- 5.03 years) were compared with a control group (28 females and 12 males) aged between 31 and 64 years old (mean 44.93 +/- 5.16 years). 95 percent of patients were HP infected, while only 47.5 percent of members of the control group were infected (p-value is less than 0.001).

conclusionConsidering the high prevalence of HP infection in patients with CSX in our sample and probable causative effect of chronic infection in vascular diseases, we believe that there is a probable role for HP infection in the pathogenesis of CSX.

Indexed as

AdultAgedCase-Control StudiesChest PainComorbidityFemaleHelicobacter InfectionsHelicobacter pyloriHumansMaleMicrovascular AnginaMiddle AgedRisk AssessmentRisk Factors

Identifiers

PMID16865212
OpenAlexW2744291245

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.