SynthesisPediatric radiology2006
Cancer risks following diagnostic and therapeutic radiation exposure in children.
Synthesis in Pediatric radiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 203 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
XFM: (X-ray Fused With MRI) Guided Cardiac Catheterization
Radiation-Free Heart Catheterization Using MRI
MRI Assessment of Arrythmia Ablation Lesions
Who cites it
203 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Cancer Effects of Low to Moderate Doses of Ionizing Radiation in Young People with Cancer-Predisposing Conditions: A Systematic Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2022Pooled it
- Outcomes of different radioprotective precautions in children undergoing dental radiography: a systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2020Pooled it
- The role of spinal angiography in the evaluation and treatment of pediatric spinal vascular pathology: a case series and systematic review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020Pooled it
- What is the best therapeutic approach to a pediatric patient with a deep-seated brain AVM?Neurosurgical review · 2019Pooled it
- Whole-body diffusion-weighted magnetic resonance imaging versus FDG-PET/CT for initial lymphoma staging: systematic review on diagnostic test accuracy studies.Sao Paulo medical journal = Revista paulista de medicinaPooled it
- Whole-body MRI for initial staging of paediatric lymphoma: prospective comparison to an FDG-PET/CT-based reference standard.European radiology · 2014Trial
- Cumulative radiation exposure from repeated CT imaging in hospitalised COVID-19 patients: Does it matter?European journal of radiology open · 2026Article
- Identifying optimal dose head CT acquisition techniques through cluster analysis from 904,209 scans.European radiology · 2026Article
- Multi-omics characterization of radiation-induced cerebellar remodeling and tumorigenic transcriptional programs.Neoplasia (New York, N.Y.) · 2026Article
- The necessity of CT/CTA scans on pediatric cerebrovascular injury after blunt trauma - a single center study.BMC emergency medicine · 2026Observational
- Article
- Intra-Individual variation in radiation dose of pediatric head CT: implications for dose optimization.Neuroradiology · 2026Observational
- Multicenter, randomized controlled study evaluating percutaneous and non-fluoroscopic procedure of atrial septal defects-study protocol of the PANASD randomized controlled trial.American heart journal plus : cardiology research and practice · 2026Article
- Outcomes in children receiving single-fraction Gamma Knife radiosurgery for arteriovenous malformation.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Diagnostic reference level curves for paediatric fluoroscopic imaging in the Netherlands.European radiology · 2026Article
- Analysis of Pediatric Cervical Spine Injury Evaluation Workflow in the Emergency Department.Journal of the American College of Emergency Physicians open · 2026Article
- The necessity of CT scans on pediatric carotid injury after blunt trauma - An analysis of the traumaregister DGUEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- The Role of Bedside Ultrasonography in Neonatal Central Venous Access Applications.Sisli Etfal Hastanesi tip bulteni · 2026Review
- Computed Tomography Diagnostic Reference Levels Worldwide and in Jordan: Implications for Patient Dose Reduction.Drug, healthcare and patient safety · 2026Review
- Multi-task learning for classification and prediction of adolescent idiopathic scoliosis based on fringe-projection three-dimensional imaging.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
143 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
1 author.
Funding
Abstract
The growing use of interventional and fluoroscopic imaging in children represents a tremendous benefit for the diagnosis and treatment of benign conditions. Along with the increasing use and complexity of these procedures comes concern about the cancer risk associated with ionizing radiation exposure to children. Children are considerably more sensitive to the carcinogenic effects of ionizing radiation than adults, and children have a longer life expectancy in which to express risk. Numerous epidemiologic cohort studies of childhood exposure to radiation for treatment of benign diseases have demonstrated radiation-related risks of cancer of the thyroid, breast, brain and skin, as well as leukemia. Many fewer studies have evaluated cancer risk following diagnostic radiation exposure in children. Although radiation dose for a single procedure might be low, pediatric patients often receive repeated examinations over time to evaluate their conditions, which could result in relatively high cumulative doses. Several cohort studies of girls and young women subjected to multiple diagnostic radiation exposures have been informative about increased mortality from breast cancer with increasing radiation dose, and case-control studies of childhood leukemia and postnatal diagnostic radiation exposure have suggested increased risks with an increasing number of examinations. Only two long-term follow-up studies of cancer following cardiac catheterization in childhood have been conducted, and neither reported an overall increased risk of cancer. Most cancers can be induced by radiation, and a linear dose-response has been noted for most solid cancers. Risks of radiation-related cancer are greatest for those exposed early in life, and these risks appear to persist throughout life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.