ArticleBone marrow transplantation2006
Nephrotic syndrome associated with chronic graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
Article in Bone marrow transplantation, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.
- Rituximab therapy for membranous nephropathy: a systematic review.Clinical journal of the American Society of Nephrology : CJASN · 2009Pooled it
- Steroid-resistant nephrotic syndrome due to renal-limited thrombotic microangiopathy and membranous nephropathy after allogeneic hematopoietic stem cell transplantation successfully treated with calcineurin inhibitors.International journal of hematology · 2025Article
- Allogeneic T cells cause acute renal injury after hematopoietic cell transplantation.Blood advances · 2023Article
- Kidney Biopsy Findings Among Allogenic Hematopoietic Stem Cell Transplant Recipients With Kidney Injury: A Case Series.Kidney medicine · 2023Article
- Clinico-pathological correlations and outcomes ofClinical kidney journal · 2023Article
- Chronic Graft-versus-host Disease-associated Membranous Nephropathy Following Bone Marrow Transplantation, Successfully Treated with Rituximab.Internal medicine (Tokyo, Japan) · 2023Article
- Association of HLA Typing and Alloimmunity With Posttransplantation Membranous Nephropathy: A Multicenter Case Series.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2020Article
- [Clinical analysis of six cases with theZhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2018Article
- Mini-review of kidney disease following hematopoietic stem cell transplant .Clinical nephrology · 2018Review
- Membranous nephropathy succeeding autologous hematopoietic stem cell transplant: a case report.BMC nephrology · 2018Article
- Acute Renal Graft-Versus-Host Disease in a Murine Model of Allogeneic Bone Marrow Transplantation.Cell transplantation · 2017Article
- Renal dysfunction following bone marrow transplantation.Journal of nephrology · 2017Review
- Renal pathology in hematopoietic cell transplant recipients: a contemporary biopsy, nephrectomy, and autopsy series.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2016Article
- Haematological malignancies and acute kidney injury requiring nephrology consultation: challenging the worst of the worst.Clinical kidney journal · 2016Article
- Long-term remission of HSCT-related NS after a second allogenic stem cell transplant.Pediatric nephrology (Berlin, Germany) · 2016Article
- Membranous nephropathy in autologous hematopoietic stem cell transplant: autologous graft-versus-host disease or autoimmunity induction?Clinical kidney journal · 2015Article
- Regulation of pulmonary graft-versus-host disease by IL-26+CD26+CD4 T lymphocytes.Journal of immunology (Baltimore, Md. : 1950) · 2015Article
- Chronic GVHD and concurrent new-onset nephrotic syndrome in allogeneic transplant recipients. Incidence, pattern and therapeutic outcomes.Bone marrow transplantation · 2015Article
- Chronic kidney disease after autologous stem cell transplantation: analysis of a single center experience.International urology and nephrology · 2014Article
- Acute graft-versus-host disease of the kidney in allogeneic rat bone marrow transplantation.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic graft-versus-host disease (cGVHD) is the most common late complication of allogeneic hematopoietic cell transplantation (HCT) causing significant morbidity and mortality. The kidneys are not considered a target organ for cGVHD in humans, although animal models show renal damage. Renal involvement in patients with cGVHD, presenting as nephrotic syndrome (NS), has rarely been reported in patients who received allogeneic transplantation. Herein we describe, by far, the largest series of nine patients with NS associated with cGVHD, including two patients who received a reduced-intensity regimen. Pathological features of membranous nephropathy were the most common finding on renal biopsy. The clinical course of the NS was temporally associated with the classical features of cGVHD in all but one of the nine cases. The clinicopathologic features of NS in our series as well as reports in the literature demonstrate an immunopathologic process typical of antibody-mediated damage consistent with cGVHD. Treatment directed against antibody-mediated damage, such as anti-B-cell antibody may play an important role in ameliorating NS associated with cGVHD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.