ArticleMedical care2006
Inappropriate drug use and risk of transition to nursing homes among community-dwelling older adults.
Article in Medical care, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Inappropriate medication use among the elderly: a systematic review of administrative databases.BMC geriatrics · 2011Pooled it
- Comparative Effectiveness of Medication Therapy Management Eligibility Criteria Across Racial/Ethnic Groups.Journal of the American Geriatrics Society · 2019Article
- Predictive Value Positive of MTM Eligibility Criteria under MMA and ACA in Identifying Individuals with Medication Utilization Issues.Journal of pharmaceutical health services research : an official journal of the Royal Pharmaceutical Society of Great Britain · 2018Article
- Potentially Inappropriate Medications and the Time to Full Functional Recovery After Hip Fracture.Drugs & aging · 2017Article
- Potentially Inappropriate Medication and Health Care Outcomes: An Instrumental Variable Approach.Health services research · 2016Article
- Trends in Prevalence and Determinants of Potentially Inappropriate Prescribing in the United States: 2007 to 2012.Journal of the American Geriatrics Society · 2016Article
- Antipsychotic Use and Risk of Nursing Home Admission Among Dual-Eligible Medicare Beneficiaries: A Propensity-Matched Study.Drugs - real world outcomes · 2015Article
- Increased health service utilization costs in the year prior to institutionalization: findings from the canadian study of health and aging.Canadian geriatrics journal : CGJ · 2014Article
- Article
- The use of START/STOPP criteria for elderly patients in primary care.TheScientificWorldJournal · 2013Article
- Explicit criteria for potentially inappropriate medications to reduce the risk of adverse drug reactions in elderly people: from Beers to STOPP/START criteria.Drug safety · 2012Review
- Potentially inappropriate medications in geriatric outpatients with polypharmacy: application of six sets of published explicit criteria.British journal of clinical pharmacology · 2011Article
- Potentially inappropriate medication use among Finnish non-institutionalized people aged ≥65 years: a register-based, cross-sectional, national study.Drugs & aging · 2011Article
- Comparison of published explicit criteria for potentially inappropriate medications in older adults.Drugs & aging · 2010Review
- Association of antipsychotic use with hospital events and mortality among medicare beneficiaries residing in long-term care facilities.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2009Article
- The clinical implications of ageing for rational drug therapy.European journal of clinical pharmacology · 2008Review
- Validation of a method for identifying nursing home admissions using administrative claims.BMC health services research · 2007Article
- Higher Predictive Value Positive for MMA Than ACA MTM Eligibility Criteria Among Racial and Ethnic Minorities: An Observational Study.Inquiry : a journal of medical care organization, provision and financingObservational
- Central nervous system-active medication polypharmacy and risk for nursing home admission among adults with early-onset dementia: A retrospective cohort study.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundAdverse events from inappropriate medications are preventable risk factors for nursing home admissions.
objectiveWe sought to investigate the relationship between inappropriate medications in older adults and transitions to nursing home.
methodsA retrospective cohort of Medicare beneficiaries with employer-sponsored supplemental health insurance was analyzed using a longitudinal data set of Medicare supplemental insurance claims. After a baseline year with no nursing home admissions, subjects were followed until the first month of transition to nursing home, loss to follow-up, or the end of the 24-month follow-up period. Survival analysis was used to compare the risk of nursing home transition among those with and without inappropriate drug use in the previous 3 months.
resultsOf the 487,383 subjects in the cohort, 22,042 (4.5%) had a nursing home admission. Use of inappropriate drugs was associated with a 31% increase in risk of nursing home admission, compared with no use of inappropriate drugs (adjusted relative risk 1.31, 99% confidence interval [CI] 1.26-1.36). Analyses of individual drug classes showed the risk of nursing home admission was similar, or lower, for inappropriate drugs versus other drugs of the same class. For example, the relative risk of nursing home admission was 2.34 (99% CI 2.20-2.47) for inappropriate narcotics and 2.68 (99% CI 2.55-2.82) for other narcotics, compared with no narcotic use.
conclusionInappropriate drug use was associated with increased risk of nursing home transition, but the increased risk may be explained by underlying patient conditions for which the drugs were prescribed rather than the inappropriate drug.
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