ArticleInfection and immunity2006
Regulation of murine dendritic cell immune responses by Helicobacter felis antigen.
Article in Infection and immunity, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 21 citations in OpenAlex.
- Helicobacter-stimulated IL-10-producing B cells suppress differentiation of lipopolysaccharide/Helicobacter felis-activated stimulatory dendritic cells.Turkish journal of biology = Turk biyoloji dergisi · 2021Article
- A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium.Cellular and molecular gastroenterology and hepatology · 2019Article
- Differential inflammatory response to Helicobacter pylori infection: etiology and clinical outcomes.Journal of inflammation research · 2015Review
- Lactic acid bacteria strains exert immunostimulatory effect on H. pylori-induced dendritic cells.Journal of immunology research · 2015Article
- The role of spartin and its novel ubiquitin binding region in DALIS occurrence.Molecular biology of the cell · 2014Article
- Rapid interaction of Helicobacter pylori with microvilli of the polar human gastric epithelial cell line NCI-N87.Anatomical record (Hoboken, N.J. : 2007) · 2013Article
- IRAK-M expression limits dendritic cell activation and proinflammatory cytokine production in response to Helicobacter pylori.PloS one · 2013Article
- Helicobacter pylori induces in-vivo expansion of human regulatory T cells through stimulating interleukin-1β production by dendritic cells.Clinical and experimental immunology · 2012Article
- Enhanced antitumor effects of a dendritic cell vaccine transfected with gastric cancer cell total RNA carrying the 4-1BBL gene in vitro.Experimental and therapeutic medicine · 2012Article
- Lack of genetic influence on the innate inflammatory response to helicobacter infection of the gastric mucosa.Frontiers in immunology · 2012Article
- TLR2-dependent modulation of dendritic cells by LT-IIa-B5, a novel mucosal adjuvant derived from a type II heat-labile enterotoxin.Journal of leukocyte biology · 2011Article
- Article
- Human primary gastric dendritic cells induce a Th1 response to H. pylori.Mucosal immunology · 2010Article
- Helicobacter pylori immune escape is mediated by dendritic cell-induced Treg skewing and Th17 suppression in mice.Gastroenterology · 2010Article
- Helicobacter pylori stimulates dendritic cells to induce interleukin-17 expression from CD4+ T lymphocytes.Infection and immunity · 2010Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Helicobacter infections are present in approximately 50% of humans, causing severe illnesses such as gastritis and malignancies. Dendritic cells (DC) are critical antigen-presenting cells which link innate and adaptive immune responses. The mechanism of dendritic cell regulation in Helicobacter-induced gastritis is poorly understood. These studies characterized DC isolated from the lamina propria of Helicobacter-infected mice and analyzed innate and adaptive immune responses elicited by Helicobacter antigen (Ag)-pulsed DC. The presence of DC was elevated in the gastric lamina propria infiltrate of infected mice in comparison with controls. After treatment with Helicobacter felis Ag, DC were polarized to secrete interleukin-6 as the dominant cytokine. In the presence of DC and Helicobacter Ag, responder allogeneic T cells in culture exhibited limited cell division. We suggest that the response of DC and T cells to Helicobacter Ag is critical to the chronic persistence of Helicobacter-induced gastritis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.