ArticlePlanta2006
Gastrodia anti-fungal protein from the orchid Gastrodia elata confers disease resistance to root pathogens in transgenic tobacco.
Article in Planta, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Whole genome sequencing and analysis of the symbiotic Armillaria gallica M3 with Gastrodia elata.BMC genomics · 2025Article
- Ectopic Expression ofJournal of fungi (Basel, Switzerland) · 2023Article
- Genetic Transformation ofPlants (Basel, Switzerland) · 2022Article
- Review
- GelFAP: Gene Functional Analysis Platform forFrontiers in plant science · 2020Article
- Remusatia vivipara lectin and Sclerotium rolfsii lectin interfere with the development and gall formation activity of Meloidogyne incognita in transgenic tomato.Transgenic research · 2019Article
- Current achievements and future directions in genetic engineering of European plum (Prunus domestica L.).Transgenic research · 2018Review
- The Gastrodia elata genome provides insights into plant adaptation to heterotrophy.Nature communications · 2018Article
- Article
- Insights into animal and plant lectins with antimicrobial activities.Molecules (Basel, Switzerland) · 2015Review
- Fusarium oxysporum triggers tissue-specific transcriptional reprogramming in Arabidopsis thaliana.PloS one · 2015Article
- The mannose-binding lectin gene FaMBL1 is involved in the resistance of unripe strawberry fruits to Colletotrichum acutatum.Molecular plant pathology · 2014Article
- A secreted protein with plant-specific cysteine-rich motif functions as a mannose-binding lectin that exhibits antifungal activity.Plant physiology · 2014Article
- Gene expression in mycorrhizal orchid protocorms suggests a friendly plant-fungus relationship.Planta · 2014Article
- Tobacco leaf spot and root rot caused by Rhizoctonia solani Kühn.Molecular plant pathology · 2011Review
- The pepper mannose-binding lectin gene CaMBL1 is required to regulate cell death and defense responses to microbial pathogens.Plant physiology · 2011Article
- Expression and purification of Zantedeschia aethiopica agglutinin in Escherichia coli.Molecular biology reports · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diseases of agricultural crops are caused by pathogens from several higher-order phylogenetic lineages including fungi, straminipila, eubacteria, and metazoa. These pathogens are commonly managed with pesticides due to the lack of broad-spectrum host resistance. Gastrodia anti-fungal protein (GAFP; gastrodianin) may provide a level of broad-spectrum resistance due to its documented anti-fungal activity in vitro and structural similarity to insecticidal lectins. We transformed tobacco (Nicotiana tabacum cv. Wisconsin 38) with GAFP-1 and challenged transformants with agriculturally important plant pathogens from several higher-order lineages including Rhizoctonia solani (fungus), Phytophthora nicotianae (straminipile), Ralstonia solanacearum (eubacterium), and Meloidogyne incognita (metazoan). Quantitative real-time PCR and western blotting analysis indicated that GAFP-1 was transcribed and translated in transgenic lines. When challenged by R. solani and P. nicotianae, GAFP-1 expressing lines had reduced symptom development and improved plant vigor compared to non-transformed and empty vector control lines. These lines also exhibited reduced root galling when challenged by M. incognita. Against R. solanacearum expression of GAFP-1 neither conferred resistance, nor exacerbated disease development. These results indicate that heterologous expression of GAFP-1 can confer enhanced resistance to a diverse set of plant pathogens and may be a good candidate gene for the development of transgenic, root-disease-resistant crops.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.