Evidence map›Paper›PMID 16855984›Full record

SynthesisThe Cochrane database of systematic reviews2006

Containment strategies for people with serious mental illness.

S Muralidharan, M Fenton

Abstract readSystematic Review
In one paragraph

Synthesis in The Cochrane database of systematic reviews, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 15 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Pooled it
  8. De-escalation techniques for psychosis-induced aggression or agitation.The Cochrane database of systematic reviews · 2017
    Pooled it
  9. Droperidol for psychosis-induced aggression or agitation.The Cochrane database of systematic reviews · 2016
    Pooled it
  10. Haloperidol for long-term aggression in psychosis.The Cochrane database of systematic reviews · 2016
    Pooled it
  11. Haloperidol plus promethazine for psychosis-induced aggression.The Cochrane database of systematic reviews · 2016
    Pooled it
  12. Pooled it
  13. Pooled it
  14. Chlorpromazine for psychosis induced aggression or agitation.The Cochrane database of systematic reviews · 2010
    Pooled it
  15. Pooled it
  16. Trial
  17. Article
  18. Review
  19. Article
  20. Acute psychiatric care: approaches to increasing the range of services and improving access and quality of care.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

S MuralidharanMental Health NHS Trust, Cambridgeshire and Peterborough Partnership, Day Activity Centre, Edith Cavall Hospital, Peterborough, UK PE29 9GZ. drsudha_m@yahoo.com
M Fenton

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe management of acutely disturbed people during periods of psychiatric crisis poses a particular challenge for mental health professionals. The challenge is to maintain safety while providing a safe and therapeutic environment. Non-pharmaceutical methods currently used to accomplish this include special observations, de-escalation, behavioural contracts and locking doors.

objectivesTo compare the effects of various strategies used to contain acutely disturbed people during periods of psychiatric crisis (excluding seclusion and restraint and the use of 'as prescribed medication). SEARCH STRATEGY: For the 2006 update of this review, we searched the Ovid interface of CINAHL, CENTRAL and The Schizophrenia Groups register, EMBASE, MEDLINE, PsycINFO. SELECTION CRITERIA: Relevant randomised controlled trials involving people hospitalised with serious mental illness, comparing any non-pharmacological interventions aimed at containing people who were at risk of harming themselves or others, (such as those approaches that change observation levels, lock wards, manage staff patient ratios, use de-escalation techniques or behavioural contracts). DATA COLLECTION AND ANALYSIS: Trials would have been reliably quality assessed and data extracted. Relative risks (RR) and 95% confidence intervals (CI) would have been calculated with a random effects model. Where possible, numbers needed to treat and harm (NNT, NNH) would have been estimated. MAIN

resultsThe initial 1999 search identified over 2000 reports and the update search of 2006, an additional 2808 reports. Of these, only six seemed to have the potential to be relevant, but once they were obtained it was clear they could not be included. None focused upon non-pharmacological methods for containment of violence or self harm in people with serious mental illness. AUTHORS'

conclusionsCurrent non-pharmacological approaches to containment of disturbed or violent behaviour are not supported by evidence from controlled studies. Clinical practice is based on evidence that is not derived from trials and continued practice entirely outside of well designed, conducted and reported randomised studies is difficult to justify.

Indexed as

AggressionCrisis InterventionHumansMental DisordersRisk ManagementSelf-Injurious BehaviorViolence

Identifiers

PMID16855984
PMCPMC11384505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.