SynthesisThe Cochrane database of systematic reviews2006
Containment strategies for people with serious mental illness.
Synthesis in The Cochrane database of systematic reviews, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 15 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 15 syntheses or guidelines pooled it.
- Cognitive behavioural therapy plus standard care versus standard care for persistent aggressive behaviour or agitation in people with schizophrenia.The Cochrane database of systematic reviews · 2023Pooled it
- [Open doors in psychiatric hospitals : An overview of empirical findings].Der Nervenarzt · 2019Pooled it
- Effects of Seclusion and Restraint in Adult Psychiatry: A Systematic Review.Frontiers in psychiatry · 2019Pooled it
- De-escalation techniques for managing non-psychosis induced aggression in adults.The Cochrane database of systematic reviews · 2018Pooled it
- Risperidone for psychosis-induced aggression or agitation (rapid tranquillisation).The Cochrane database of systematic reviews · 2018Pooled it
- Aripiprazole (intramuscular) for psychosis-induced aggression or agitation (rapid tranquillisation).The Cochrane database of systematic reviews · 2018Pooled it
- Haloperidol for psychosis-induced aggression or agitation (rapid tranquillisation).The Cochrane database of systematic reviews · 2017Pooled it
- De-escalation techniques for psychosis-induced aggression or agitation.The Cochrane database of systematic reviews · 2017Pooled it
- Droperidol for psychosis-induced aggression or agitation.The Cochrane database of systematic reviews · 2016Pooled it
- Haloperidol for long-term aggression in psychosis.The Cochrane database of systematic reviews · 2016Pooled it
- Haloperidol plus promethazine for psychosis-induced aggression.The Cochrane database of systematic reviews · 2016Pooled it
- Health service use and costs associated with aggressiveness or agitation and containment in adult psychiatric care: a systematic review of the evidence.BMC psychiatry · 2015Pooled it
- Zuclopenthixol acetate for acute schizophrenia and similar serious mental illnesses.The Cochrane database of systematic reviews · 2012Pooled it
- Chlorpromazine for psychosis induced aggression or agitation.The Cochrane database of systematic reviews · 2010Pooled it
- A systematic review of the international published literature relating to quality of institutional care for people with longer term mental health problems.BMC psychiatry · 2009Pooled it
- Study protocol for a cluster randomised controlled trial to assess the effectiveness of user-driven intervention to prevent aggressive events in psychiatric services.BMC psychiatry · 2017Trial
- Patient Perspectives on Open-Door Policies in Psychiatry: Mixed Methods Study.Journal of medical Internet research · 2025Article
- A Comprehensive Understanding of Psychomotor Agitation: From Causes to Hospital Care.Current neuropharmacology · 2025Review
- Joint Crisis Plan in Mental Health Settings: A Reflective Process More than an Intervention Tool?Healthcare (Basel, Switzerland) · 2024Article
- Acute psychiatric care: approaches to increasing the range of services and improving access and quality of care.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe management of acutely disturbed people during periods of psychiatric crisis poses a particular challenge for mental health professionals. The challenge is to maintain safety while providing a safe and therapeutic environment. Non-pharmaceutical methods currently used to accomplish this include special observations, de-escalation, behavioural contracts and locking doors.
objectivesTo compare the effects of various strategies used to contain acutely disturbed people during periods of psychiatric crisis (excluding seclusion and restraint and the use of 'as prescribed medication). SEARCH STRATEGY: For the 2006 update of this review, we searched the Ovid interface of CINAHL, CENTRAL and The Schizophrenia Groups register, EMBASE, MEDLINE, PsycINFO. SELECTION CRITERIA: Relevant randomised controlled trials involving people hospitalised with serious mental illness, comparing any non-pharmacological interventions aimed at containing people who were at risk of harming themselves or others, (such as those approaches that change observation levels, lock wards, manage staff patient ratios, use de-escalation techniques or behavioural contracts). DATA COLLECTION AND ANALYSIS: Trials would have been reliably quality assessed and data extracted. Relative risks (RR) and 95% confidence intervals (CI) would have been calculated with a random effects model. Where possible, numbers needed to treat and harm (NNT, NNH) would have been estimated. MAIN
resultsThe initial 1999 search identified over 2000 reports and the update search of 2006, an additional 2808 reports. Of these, only six seemed to have the potential to be relevant, but once they were obtained it was clear they could not be included. None focused upon non-pharmacological methods for containment of violence or self harm in people with serious mental illness. AUTHORS'
conclusionsCurrent non-pharmacological approaches to containment of disturbed or violent behaviour are not supported by evidence from controlled studies. Clinical practice is based on evidence that is not derived from trials and continued practice entirely outside of well designed, conducted and reported randomised studies is difficult to justify.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.