ArticleNucleic acids research2006
Chromosome-wide identification of novel imprinted genes using microarrays and uniparental disomies.
Article in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Exploring the interplay between DHCR7, vitamin D deficiency, and type 2 diabetes mellitus (T2DM): a systematic review.Molecular biology reports · 2024Pooled it
- Pooled it
- Dynamic allelic expression in mouse mammary glands across the adult developmental cycle.Nucleic acids research · 2025Article
- Mom genes and dad genes: genomic imprinting in the regulation of social behaviors.Epigenomics · 2025Review
- Imprinted Genes: Genomic Conservation, Transcriptomic Dynamics and Phenomic Significance in Health and Diseases.International journal of biological sciences · 2023Review
- Loss of imprinting of the Igf2-H19 ICR1 enhances placental endocrine capacity via sex-specific alterations in signalling pathways in the mouse.Development (Cambridge, England) · 2022Article
- Article
- Article
- Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage.PLoS genetics · 2018Article
- Parent-of-Origin Effects of the APOB Gene on Adiposity in Young Adults.PLoS genetics · 2015Article
- Allelic Imbalance Is a Prevalent and Tissue-Specific Feature of the Mouse Transcriptome.Genetics · 2015Article
- Article
- Review
- The impact of assisted reproductive technologies on genomic imprinting and imprinting disorders.Current opinion in obstetrics & gynecology · 2014Review
- Transcriptome-wide investigation of genomic imprinting in chicken.Nucleic acids research · 2014Article
- DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation.BMC genomics · 2013Article
- Metabolic changes in DYT11 myoclonus-dystonia.Neurology · 2013Article
- Empirical testing of hypotheses about the evolution of genomic imprinting in mammals.Frontiers in neuroanatomy · 2013Article
- A survey of tissue-specific genomic imprinting in mammals.Molecular genetics and genomics : MGG · 2012Review
- Critical evaluation of imprinted gene expression by RNA-Seq: a new perspective.PLoS genetics · 2012Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Genomic imprinting refers to a specialized form of epigenetic gene regulation whereby the expression of a given allele is dictated by parental origin. Defining the extent and distribution of imprinting across genomes will be crucial for understanding the roles played by imprinting in normal mammalian growth and development. Using mice carrying uniparental disomies or duplications, microarray screening and stringent bioinformatics, we have developed the first large-scale tissue-specific screen for imprinted gene detection. We quantify the stringency of our methodology and relate it to previous non-tissue-specific large-scale studies. We report the identification in mouse of four brain-specific novel paternally expressed transcripts and an additional three genes that show maternal expression in the placenta. The regions of conserved linkage in the human genome are associated with the Prader-Willi Syndrome (PWS) and Beckwith-Wiedemann Syndrome (BWS) where imprinting is known to be a contributing factor. We conclude that large-scale systematic analyses of this genre are necessary for the full impact of genomic imprinting on mammalian gene expression and phenotype to be elucidated.
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