ArticleNucleic acids research2006
An open-access long oligonucleotide microarray resource for analysis of the human and mouse transcriptomes.
Article in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed.
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- TAF15 is important for cellular proliferation and regulates the expression of a subset of cell cycle genes through miRNAs.Oncogene · 2013Article
- Adenosine stimulates the migration of human endothelial progenitor cells. Role of CXCR4 and microRNA-150.PloS one · 2013Article
- Skeletal muscle alterations and exercise performance decrease in erythropoietin-deficient mice: a comparative study.BMC medical genomics · 2012Article
- p63 regulates human keratinocyte proliferation via MYC-regulated gene network and differentiation commitment through cell adhesion-related gene network.The Journal of biological chemistry · 2012Article
- Epithelial-mesenchymal-transition-like and TGFβ pathways associated with autochthonous inflammatory melanoma development in mice.PloS one · 2012Article
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- Genome-wide transcriptional response of the archaeon Thermococcus gammatolerans to cadmium.PloS one · 2012Article
- Transforming growth factor β receptor 1 is a new candidate prognostic biomarker after acute myocardial infarction.BMC medical genomics · 2011Article
- A transcriptome signature distinguished sporadic from postradiotherapy radiation-induced sarcomas.Carcinogenesis · 2011Article
- miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity.Cell death and differentiation · 2011Article
- Strategy to find molecular signatures in a small series of rare cancers: validation for radiation-induced breast and thyroid tumors.PloS one · 2011Article
- SigReannot-mart: a query environment for expression microarray probe re-annotations.Database : the journal of biological databases and curation · 2011Article
- An optimized protocol for microarray validation by quantitative PCR using amplified amino allyl labeled RNA.BMC genomics · 2010Article
- Modulation of gene expression in endothelial cells by hyperlipaemic postprandial serum from healthy volunteers.Genes & nutrition · 2010Article
- Integrated protein network and microarray analysis to identify potential biomarkers after myocardial infarction.Functional & integrative genomics · 2010Article
- Brain transcriptional stability upon prion protein-encoding gene invalidation in zygotic or adult mouse.BMC genomics · 2010Article
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Authors and funding
21 authors.
Funding
Abstract
Two collections of oligonucleotides have been designed for preparing pangenomic human and mouse microarrays. A total of 148,993 and 121,703 oligonucleotides were designed against human and mouse transcripts. Quality scores were created in order to select 25,342 human and 24,109 mouse oligonucleotides. They correspond to: (i) a BLAST-specificity score; (ii) the number of expressed sequence tags matching each probe; (iii) the distance to the 3' end of the target mRNA. Scores were also used to compare in silico the two microarrays with commercial microarrays. The sets described here, called RNG/MRC collections, appear at least as specific and sensitive as those from the commercial platforms. The RNG/MRC collections have now been used by an Anglo-French consortium to distribute more than 3500 microarrays to the academic community. Ad hoc identification of tissue-specific transcripts and a approximately 80% correlation with hybridizations performed on Affymetrix GeneChiptrade mark suggest that the RNG/MRC microarrays perform well. This work provides a comprehensive open resource for investigators working on human and mouse transcriptomes, as well as a generic method to generate new microarray collections in other organisms. All information related to these probes, as well as additional information about commercial microarrays have been stored in a freely-accessible database called MEDIANTE.
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