Evidence map›Paper›PMID 16855252›Full record

ArticleJournal of bacteriology2006

Uropathogenic Escherichia coli strains generally lack functional Trg and Tap chemoreceptors found in the majority of E. coli strains strictly residing in the gut.

M Chelsea Lane, Amanda L Lloyd, Tiffany A Markyvech, Erin C Hagan, Harry L T Mobley

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of bacteriology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M Chelsea LaneDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.
Amanda L Lloyd
Tiffany A Markyvech
Erin C Hagan
Harry L T Mobley
University of Michigan–Ann Arbor · USUniversity of Maryland, Baltimore · US

Funding

Reciprocal Control of Motility and Adherence in UTIR01AI059722 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PEARSON, MELANIE M. · 2005 to 2024
$7.4M
MOLECULAR PATHOGENESIS OF E COLI UTIR01AI043363 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOBLEY, HARRY L. · 1998 to 2012
$3.4M
Vaccine to prevent E. coli urinary tract infectionR56AI043363 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MOBLEY, HARRY L. · 2014 to 2014
$351k
NIAID NIH HHS AI059722NIAID NIH HHS AI43363NIAID NIH HHS R01 AI043363NIAID NIH HHS R01 AI059722NIAID NIH HHS R56 AI043363
6 · The paper itself

Abstract

The prevalence and function of four chemoreceptors, Tsr, Tar, Trg, and Tap, were determined for a collection of uropathogenic, fecal-commensal, and diarrheagenic Escherichia coli strains. tar and tsr were present or functional in nearly all isolates. However, trg and tap were significantly less prevalent or functional among the uropathogenic E. coli strains (both in 6% of strains) than among fecal-commensal strains (both in > or =50% of strains) or diarrheal strains (both in > or =75% of strains) (P < 0.02).

Indexed as

ChemotaxisAmino AcidsBacteriological TechniquesBase SequenceEscherichia coliEscherichia coli InfectionsEscherichia coli ProteinsFemaleGenes, BacterialHumansMaleMembrane ProteinsMolecular Sequence DataReceptors, Cell SurfaceSequence AlignmentUreaAmino AcidsEscherichia coli ProteinsMembrane ProteinsReceptors, Cell SurfaceTap protein, E coliTrg protein, E coliUrea

Identifiers

PMID16855252
PMCPMC1540019
OpenAlexW2137166721

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.