ArticleVeterinary microbiology2006
Genetic characterization of the first chiropteran papillomavirus, isolated from a basosquamous carcinoma in an Egyptian fruit bat: the Rousettus aegyptiacus papillomavirus type 1.
Article in Veterinary microbiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Correlates of viral richness in bats (order Chiroptera).EcoHealth · 2009Pooled it
- Characterization of spontaneous gross and histologic findings in free-ranging Egyptian rousettes (Rousettus aegyptiacus) from Uganda with a review of reported pathogens.Veterinary research · 2026Article
- Article
- Origin and evolution of papillomavirus (onco)genes and genomes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2019Article
- Detection of adenovirus, papillomavirus and parvovirus in Brazilian bats of the species Artibeus lituratus and Sturnira lilium.Archives of virology · 2019Article
- Detection of Felis catus papillomavirus type 2 within multicentric basosquamous carcinoma in a domestic cat.The Journal of veterinary medical science · 2018Article
- Association of papillomavirus E6 proteins with either MAML1 or E6AP clusters E6 proteins by structure, function, and evolutionary relatedness.PLoS pathogens · 2017Article
- A single bat species in Cameroon harbors multiple highly divergent papillomaviruses in stool identified by metagenomics analysis.Virology reports · 2016Article
- Article
- Novel papillomaviruses in free-ranging Iberian bats: no virus-host co-evolution, no strict host specificity, and hints for recombination.Genome biology and evolution · 2014Article
- Article
- Virome analysis for identification of novel mammalian viruses in bat species from Chinese provinces.Journal of virology · 2012Article
- Article
- Classification of papillomaviruses (PVs) based on 189 PV types and proposal of taxonomic amendments.Virology · 2010Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The complete genomic DNA of a novel papillomavirus (PV) was isolated from a basosquamous carcinoma on the wing of an Egyptian fruit bat (Rousettus aegyptiacus). Initial short sequences of the E1 and L1 genes of this virus were retrieved by PCR with degenerate papillomavirus-specific primers, and the entire R. aegyptiacus papillomavirus type 1 (RaPV-1) DNA was then amplified by long template PCR, cloned and sequenced with a transposon insertion method. The RaPV-1 genome counts 7970 basepairs and contains the typical papillomavirus open reading frames (ORF) (E1, E2, E4, E6, E7, L1 and L2). Based on a concatenated alignment of the E1, E2, L1 and L2 open reading frames of RaPV-1 and 46 other human and animal papillomavirus type species, a neighbor-joining phylogenetic tree was constructed. This phylogenetic analysis shows that RaPV-1 has a close-to-root position in the papillomavirus evolutionary tree. Since RaPV-1 is only distantly related to other papillomaviruses (with maximally 50% nucleotide sequence identity across the L1 open reading frame), it cannot be assigned to one of the existing papillomavirus genera and therefore represents the first member of a novel, as yet unnamed, close-to-root papillomavirus genus. This is the first time a papillomavirus has been isolated and characterized from a member of the Chiroptera order.
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Registered trials
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