ArticlePLoS genetics2006
The ancestral eutherian karyotype is present in Xenarthra.
Article in PLoS genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 47 citations in OpenAlex.
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- Microchromosomes are building blocks of bird, reptile, and mammal chromosomes.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Comparative mitogenome phylogeography of two anteater genera (Zoological research · 2021Article
- Identification and characterization of satellite DNAs in two-toed sloths of the genus Choloepus (Megalonychidae, Xenarthra).Scientific reports · 2020Article
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- Chromosome painting in three-toed sloths: a cytogenetic signature and ancestral karyotype for Xenarthra.BMC evolutionary biology · 2012Article
- Review
- The genome diversity and karyotype evolution of mammals.Molecular cytogenetics · 2011Article
- Reconstruction of karyotype evolution in core Glires. I. The genome homology revealed by comparative chromosome painting.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2011Article
- Gene synteny comparisons between different vertebrates provide new insights into breakage and fusion events during mammalian karyotype evolution.BMC evolutionary biology · 2009Article
- A methodological framework for the reconstruction of contiguous regions of ancestral genomes and its application to mammalian genomes.PLoS computational biology · 2008Article
- Chromosomal instability in Afrotheria: fragile sites, evolutionary breakpoints and phylogenetic inference from genome sequence assemblies.BMC evolutionary biology · 2007Article
- Chromosome painting among Proboscidea, Hyracoidea and Sirenia: support for Paenungulata (Afrotheria, Mammalia) but not Tethytheria.Proceedings. Biological sciences · 2007Article
- Chromosome painting in the manatee supports Afrotheria and Paenungulata.BMC evolutionary biology · 2007Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Molecular studies have led recently to the proposal of a new super-ordinal arrangement of the 18 extant Eutherian orders. From the four proposed super-orders, Afrotheria and Xenarthra were considered the most basal. Chromosome-painting studies with human probes in these two mammalian groups are thus key in the quest to establish the ancestral Eutherian karyotype. Although a reasonable amount of chromosome-painting data with human probes have already been obtained for Afrotheria, no Xenarthra species has been thoroughly analyzed with this approach. We hybridized human chromosome probes to metaphases of species (Dasypus novemcinctus, Tamandua tetradactyla, and Choloepus hoffmanii) representing three of the four Xenarthra families. Our data allowed us to review the current hypotheses for the ancestral Eutherian karyotype, which range from 2n = 44 to 2n = 48. One of the species studied, the two-toed sloth C. hoffmanii (2n = 50), showed a chromosome complement strikingly similar to the proposed 2n = 48 ancestral Eutherian karyotype, strongly reinforcing it.
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