Evidence map›Paper›PMID 16847556›Full record

ArticleCellular & molecular biology letters2006

A comparison of the in vitro antimicrobial activity of liposomes containing meropenem and gentamicin.

Zuzanna Drulis-Kawa, Jerzy Gubernator, Agata Dorotkiewicz-Jach, Włodzimierz Doroszkiewicz, Arkadiusz Kozubek

Open access · hybridAbstract readComparative Study
In one paragraph

Article in Cellular & molecular biology letters, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
  2. Carrageenan-Acyclovir Complex and Its Liposomal Form.International journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Experimental Design Supported Liposomal Aztreonam Delivery:Advanced pharmaceutical bulletin · 2021
    Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zuzanna Drulis-KawaInstitute of Genetics and Microbiology, University of Wrocław, Przybyszewskiego 63/77, Wrocław, Poland. kawa@microb.uni.wroc.pl
Jerzy Gubernator
Agata Dorotkiewicz-Jach
Włodzimierz Doroszkiewicz
Arkadiusz Kozubek
University of Wrocław · PLUniversity of Business in Wrocław · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The antimicrobial activity of eight cationic, two neutral and three anionic liposome compositions containing meropenem and gentamicin was tested in vitro in broth and serum medium. The cationic formulations showed better antibacterial efficacy against both Gram-positive and Gram-negative bacteria than the anionic and neutral ones, regardless of the encapsulated drug. The most effective formulations were the cationic PC/DOPE/DOTAP 3:4:3 and PC/Chol/DOTAP 3:4:3, as the MICs with meropenem were 2 to 4 times lower than those of the free drug.

Indexed as

Anti-Bacterial AgentsBacteriaGentamicinsLiposomesMeropenemMicrobial Sensitivity TestsThienamycinsAnti-Bacterial AgentsGentamicinsLiposomesMeropenemThienamycins

Identifiers

PMID16847556
PMCPMC6472838
OpenAlexW1981891468

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.