Evidence map›Paper›PMID 16846498›Full record

Trial reportNutrition journal2006

The positive impact of red palm oil in school meals on vitamin A status: study in Burkina Faso.

Augustin N Zeba, Yves Martin Prével, Issa T Somé, Hélène F Delisle

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrition journal, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03256123 (The Effect of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East Malaysia), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03256123 nacompletednot on this mapstarted 2017, after this paper: background citation

The Effect of Biscuits Containing Red Palm Oil on School Children With Vitamin A Deficiency in West and East Malaysia

TypeinterventionalSponsorMalaysia Palm Oil BoardRan2017 to 2019Enrolled651ConditionsVitamin A Deficiency in ChildrenArmsred palm shortening group, palm shortening group
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Augustin N ZebaDepartment of Nutrition, Faculty of Medicine, Université de Montréal, C,P, 6128 succ, Centre-ville, Montréal Qc, H3C 3J7, Canada. nawidzeb@yahoo.fr
Yves Martin Prével
Issa T Somé
Hélène F Delisle

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin A (VA) deficiency is widespread in sub-Saharan Africa and school-age children are a vulnerable group. In Burkina Faso, the production and consumption of red palm oil (RPO) is being promoted as a food supplement for VA. The objective of the study was to assess the impact on serum retinol of adding RPO to school lunch in two test zones of Burkina Faso.

methodsOver one school year, 15 ml RPO was added to individual meals 3 times a week in selected primary schools in two sites. Serum retinol was measured with HPLC at baseline and exactly 12 months later to take account of seasonality. A simple pre-post test design was used in the Kaya area (north-central Burkina), where 239 pupils from 15 intervention schools were randomly selected for the evaluation. In Bogandé (eastern Burkina), 24 schools were randomised for the controlled intervention trial: 8 negative controls (G1) with only the regular school lunch; 8 positive controls (G2) where the pupils received a single VA capsule (60 mg) at the end of the school year; and 8 schools with RPO through the school year (G3). A random sample of 128 pupils in each school group took part in the evaluation.

resultsIn Kaya, serum retinol went from 0.77 +/- 0.37 micromol/L at baseline to 1.07 +/- 0.40 micromol/L one year later (p < 0.001). The rate of low serum retinol (< 0.7 micromol/L) declined from 47.2% to 13.1%. In Bogandé, serum retinol increased significantly (p < 0.001) only in the capsule and RPO groups, going from 0.77 +/- 0.28 to 0.98 +/- 0.33 micromol/L in the former, and from 0.82 +/- 0.3 to 0.98 +/- 0.33 micromol/L in the latter. The rate of low serum retinol went from 46.1 to 17.1% in the VA capsule group and from 40.4% to 14.9% in the RPO group. VA-deficient children benefited the most from the capsule or RPO. Female sex, age and height-for-age were positively associated with the response to VA capsules or RPO.

conclusionRPO given regularly in small amounts appears highly effective in the reduction of VA deficiency. RPO deserves more attention as a food supplement for VA and as a potential source of rural income in Sahelian countries.

Indexed as

Food ServicesNutritional StatusSchoolsBurkina FasoChildFemaleHumansMalePalm OilPlant OilsSeasonsVitamin APalm OilPlant OilsVitamin A

Identifiers

PMID16846498
PMCPMC1562437

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.