Evidence map›Paper›PMID 16846256›Full record

ReviewPLoS pathogens2006

Shield as signal: lipopolysaccharides and the evolution of immunity to gram-negative bacteria.

Robert S Munford, Alan W Varley

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed.

  1. Arabidopsides as Signatory Biomarkers of theInternational journal of molecular sciences · 2026
    Review
  2. Article
  3. Article
  4. Lipopolysaccharides fromFrontiers in molecular biosciences · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. DissectingFrontiers in cellular and infection microbiology · 2022
    Article
  11. Review
  12. Observational
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert S MunfordDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA. Robert.munford@utsouthwestern.edu
Alan W Varley

Funding

INTERACTIONS OF ENDOTOXIN WITH PLASMA AND CELLSR01AI018188 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI VARLEY, ALAN WAYNE · 1985 to 2011
$3.9M
INTERACTIONS OF ENDOTOXIN WITH PLASMA AND CELLSR37AI018188 · NIAID · UNIVERSITY OF TEXAS SW MED CTR/DALLAS · PI MUNFORD, ROBERT S · 1992 to 2001
$729k
Interactions of Endotoxin with Plasma and CellsR56AI018188 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI MUNFORD, ROBERT S · 2007 to 2007
$523k
NIAID NIH HHS AI18188
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Biological EvolutionAcylationAnimalsCarboxylic Ester HydrolasesGram-Negative BacteriaGram-Negative Bacterial InfectionsHumansHydrolysisImmunity, InnateImmunity, MucosalLipid ALipopolysaccharidesToll-Like Receptor 4acyloxyacyl hydrolaseCarboxylic Ester HydrolasesLipid ALipopolysaccharidesToll-Like Receptor 4

Identifiers

PMID16846256
PMCPMC1483240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.