ArticleJournal of Zhejiang University. Science. B2006
Studies on Pongamia pinnata (L.) Pierre leaves: understanding the mechanism(s) of action in infectious diarrhea.
Article in Journal of Zhejiang University. Science. B, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 78 citations in OpenAlex.
- Anti-inflammatory Potential ofAnti-inflammatory & anti-allergy agents in medicinal chemistry · 2026Review
- What is the state of the art on traditional medicine interventions for zoonotic diseases in the Indian subcontinent? A scoping review of the peer-reviewed evidence base.BMC complementary medicine and therapies · 2024Article
- Antimicrobial Secondary Metabolites from the Mangrove Plants of Asia and the Pacific.Marine drugs · 2022Review
- In silico validation of the indigenous knowledge of the herbal medicines among tribal communities in Sathyamangalam wildlife sanctuary, India.Journal of traditional and complementary medicine · 2019Article
- Assessment of genetic characteristics ofBiotechnology, biotechnological equipment · 2015Article
- Acute Toxicity Investigation and Anti-diarrhoeal Effect of the Chloroform-Methanol Extract of the Leaves of Persea americana.Iranian journal of pharmaceutical research : IJPR · 2014Article
- Can scientific evidence support using Bangladeshi traditional medicinal plants in the treatment of diarrhoea? A review on seven plants.Nutrients · 2013Review
- In Vivo Effects of Cagaita (Eugenia dysenterica, DC.) Leaf Extracts on Diarrhea Treatment.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Newer insights into the mechanism of action of Psidium guajava L. leaves in infectious diarrhoea.BMC complementary and alternative medicine · 2010Article
- Molecular marker-based characterization in candidate plus trees of Pongamia pinnata, a potential biodiesel legume.AoB PLANTS · 2010Article
- Studies on the antidiarrhoeal activity of Aegle marmelos unripe fruit: validating its traditional usage.BMC complementary and alternative medicine · 2009Article
- Therapeutic significance and pharmacological activities of antidiarrheal medicinal plants mention in Ayurveda: A review.Journal of intercultural ethnopharmacologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While data are available on the effect of medicinal plants on intestinal motility and their antibacterial action, there is a paucity of information on their mode of action on various aspects of diarrheal pathogenicity, namely colonization to intestinal epithelial cells and production/action of enterotoxins. Crude decoction of dried leaves of Pongamia pinnata was evaluated for its antimicrobial (antibacterial, antigiardial and antirotaviral) effect; and its effect on production and action of enterotoxins (cholera toxin, CT; Escherichia coli labile toxin, LT; and E. coli stable toxin, ST); and adherence of enteropathogenic E. coli and invasion of enteroinvasive E. coli and Shigella flexneri to epithelial cells. The decoction had no antibacterial, antigiardial and antirotaviral activity, but reduced production of CT and bacterial invasion to epithelial cells. The observed results indicated that the crude decoction of P. pinnata has selective antidiarrheal action with efficacy against cholera and enteroinvasive bacterial strains causing bloody diarrheal episodes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.