ArticlePlant molecular biology2006
The putative SWI/SNF complex subunit BRAHMA activates flower homeotic genes in Arabidopsis thaliana.
Article in Plant molecular biology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 141 citations in OpenAlex.
- BRAHMA represses STOP1-NRT1.1 module to control plant rhizosphere alkalization and acid stress adaptation.Nature communications · 2026Article
- Identification of novel candidate gene associated with early heading on chromosome 5B in wheat mutantMolecular breeding : new strategies in plant improvement · 2025Article
- Regulation of seed germination: ROS, epigenetic, and hormonal aspects.Journal of advanced research · 2025Review
- The SAS chromatin-remodeling complex mediates inflorescence-specific chromatin accessibility for transcription factor binding.Nucleic acids research · 2025Article
- SWI/SNF-type complexes-transcription factor interplay: a key regulatory interaction.Cellular & molecular biology letters · 2025Review
- The BRAHMA-associated SWI/SNF chromatin remodeling complex controls Arabidopsis seed quality and physiology.Plant physiology · 2024Article
- Strigolactone induces D14-dependent large-scale changes in gene expression requiring SWI/SNF chromatin remodellers.The Plant journal : for cell and molecular biology · 2024Article
- Chromatin sensing: integration of environmental signals to reprogram plant development through chromatin regulators.Journal of experimental botany · 2024Review
- Molecular and structural basis of the chromatin remodeling activity by Arabidopsis DDM1.Nature communications · 2024Article
- Beyond NPK: Mineral Nutrient-Mediated Modulation in Orchestrating Flowering Time.Plants (Basel, Switzerland) · 2023Review
- Gibberellin signaling modulates flowering via the DELLA-BRAHMA-NF-YC module in Arabidopsis.The Plant cell · 2023Article
- Spotlight on Plant Bromodomain Proteins.Biology · 2023Review
- Organization, genomic targeting, and assembly of three distinct SWI/SNF chromatin remodeling complexes in Arabidopsis.The Plant cell · 2023Article
- An Overview of Molecular Basis and Genetic Modification of Floral Organs Genes: Impact of Next-Generation Sequencing.Molecular biotechnology · 2023Review
- BRM Complex in Arabidopsis Adopts ncBAF-like Composition and Requires BRD Subunits for Assembly and Stability.International journal of molecular sciences · 2023Article
- Comprehensive characterization of three classes of Arabidopsis SWI/SNF chromatin remodelling complexes.Nature plants · 2022Article
- SWI2/SNF2 chromatin remodeling ATPases SPLAYED and BRAHMA control embryo development in rice.Plant cell reports · 2022Article
- Article
- LEAFY COTYLEDONs: Connecting different stages of plant development.Frontiers in plant science · 2022Review
- Comparative Expression Profiling of Snf2 Family Genes During Reproductive Development and Stress Responses in Rice.Frontiers in plant science · 2022Article
9 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arabidopsis thaliana BRAHMA (BRM, also called AtBRM) is a SNF2 family protein homolog of Brahma, the ATPase of the Drosophila SWI/SNF complex involved in chromatin remodeling during transcription. Here we show that, in contrast to its Drosophila counterpart, BRM is not an essential gene. Thus, homozygous BRM loss of function mutants are viable but exhibit numerous defects including dwarfism, altered leaf and root development and several reproduction defects. The analysis of the progeny of self-fertilized heterozygous brm plants and reciprocal crosses between heterozygous and wild type plants indicated that disruption of BRM reduced both male and female gametophyte transmission. This was consistent with the presence of aborted ovules in the self-fertilized heterozygous flowers that contained arrested embryos predominantly at the two terminal cells stage. Furthermore, brm homozygous mutants were completely sterile. Flowers of brm loss-of-function mutants have several developmental abnormalities, including homeotic transformations in the second and third floral whorls. In accordance with these results, brm mutants present reduced levels of APETALA2, APETALA3, PISTILLATA and NAC-LIKE, ACTIVATED BY AP3/PI. We have previously shown that BRM strongly interacts with AtSWI3C. Now we extend our interaction studies demonstrating that BRM interacts weakly with AtSWI3B but not with AtSWI3A or AtSWI3D. In agreement with these results, the phenotype described in this study for brm plants is very similar to that previously described for the AtSWI3C mutant plants, suggesting that both proteins participate in the same genetic pathway or form a molecular complex.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.