Evidence map›Paper›PMID 16845085›Full record

ArticleNucleic acids research2006

PupaSuite: finding functional single nucleotide polymorphisms for large-scale genotyping purposes.

Lucía Conde, Juan M Vaquerizas, Hernán Dopazo, Leonardo Arbiza, Joke Reumers, Frederic Rousseau, Joost Schymkowitz, Joaquín Dopazo

Abstract read
In one paragraph

Article in Nucleic acids research, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Gene-by-environment effect of house dust mite on purinergic receptor P2Y12 (P2RY12) and lung function in children with asthma.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2012
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  7. Review
  8. Article
  9. Article
  10. Article
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  12. Article
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  17. Cytokine gene variations associated with trait and state anxiety in oncology patients and their family caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Article
  18. Article
  19. CRY1, CRY2 and PRKCDBP genetic variants in metabolic syndrome.Hypertension research : official journal of the Japanese Society of Hypertension · 2015
    Article
  20. Review

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lucía CondeDepartment of Bioinformatics, Centro de Investigación Príncipe Felipe (CIPF), Valencia, 46013, Spain.
Juan M Vaquerizas
Hernán Dopazo
Leonardo Arbiza
Joke Reumers
Frederic Rousseau
Joost Schymkowitz
Joaquín Dopazo

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have developed a web tool, PupaSuite, for the selection of single nucleotide polymorphisms (SNPs) with potential phenotypic effect, specifically oriented to help in the design of large-scale genotyping projects. PupaSuite uses a collection of data on SNPs from heterogeneous sources and a large number of pre-calculated predictions to offer a flexible and intuitive interface for selecting an optimal set of SNPs. It improves the functionality of PupaSNP and PupasView programs and implements new facilities such as the analysis of user's data to derive haplotypes with functional information. A new estimator of putative effect of polymorphisms has been included that uses evolutionary information. Also SNPeffect database predictions have been included. The PupaSuite web interface is accessible through http://pupasuite.bioinfo.cipf.es and through http://www.pupasnp.org.

Indexed as

Polymorphism, Single NucleotideSoftwareAlgorithmsComputer GraphicsDatabases, Nucleic AcidEvolution, MolecularGenotypeHaplotypesInternetLinkage DisequilibriumUser-Computer Interface

Identifiers

PMID16845085
PMCPMC1538854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.