ReviewJournal of the American College of Cardiology2006
Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications.
Review in Journal of the American College of Cardiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 66 citations in OpenAlex.
- Effect of olive oil phenolic compounds on the expression of blood pressure-related genes in healthy individuals.European journal of nutrition · 2017Trial
- Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.Circulation. Cardiovascular genetics · 2009Trial
- Review
- Discovering biomarkers associated and predicting cardiovascular disease with high accuracy using a novel nexus of machine learning techniques for precision medicine.Scientific reports · 2024Article
- Genomic approaches to identify and investigate genes associated with atrial fibrillation and heart failure susceptibility.Human genomics · 2023Review
- RNA-seq driven expression and enrichment analysis to investigate CVD genes with associated phenotypes among high-risk heart failure patients.Human genomics · 2021Article
- Insight into atrial fibrillation through analysis of the coding transcriptome in humans.Biophysical reviews · 2020Review
- Extra Virgin Olive Oil: Lesson from Nutrigenomics.Nutrients · 2019Review
- Network topology reveals key cardiovascular disease genes.PloS one · 2013Article
- Next steps in cardiovascular disease genomic research--sequencing, epigenetics, and transcriptomics.Clinical chemistry · 2012Review
- The emerging role of microRNAs in drug responses.Current opinion in molecular therapeutics · 2010Review
- Genomic approaches to coronary artery disease.The Indian journal of medical research · 2010Review
- Article
- FOS expression in blood as a LDL-independent marker of statin treatment.Atherosclerosis · 2010Article
- Modulation of gene expression in endothelial cells by hyperlipaemic postprandial serum from healthy volunteers.Genes & nutrition · 2010Article
- Secondary prevention strategies for coronary heart disease.Journal of thrombosis and thrombolysis · 2010Review
- Gene expression signatures diagnose influenza and other symptomatic respiratory viral infections in humans.Cell host & microbe · 2009Article
- Tobacco use induces anti-apoptotic, proliferative patterns of gene expression in circulating leukocytes of Caucasian males.BMC medical genomics · 2008Article
- Identifying the most suitable endogenous control for determining gene expression in hearts from organ donors.BMC molecular biology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although the contribution of genetics to complex cardiovascular diseases such as atherosclerosis has been accepted for quite some time, full and detailed knowledge of the individual causative genes has been elusive. With the advent of genomic technologies and methods, the necessary tools are now available to begin pinpointing the genes that contribute to disease susceptibility and progression. One approach being applied extensively in candidate gene discovery is gene expression analysis of human and animal tissues using microarrays. The genes identified by these genomic studies provide valuable insight into disease biology and represent the initial steps toward the development of diagnostic tests and therapeutic strategies that will substantially improve human health. This paper highlights the progress that has been made in using gene expression analysis cardiovascular genomic research and the potential for applying these findings in clinical medicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.