Who was studied, and how
Two numbers in the abstract
Where each one falls
Only readable comparisons vote
Where it lands on the map
70people in the Difference of Basal Insulin Titration Method in Reducing HbA1c Among Type 2 Diabetes Mellitus trial, from 2021
of them with type 2 diabetes, in this paper
The trial randomly assignedassigned by chance
evening insulin glargine plus self-titration by 1 unit/day if the fasting plasma glucose (FPG) was > 5.5 mmol/l
conventional therapy with physician adjustment of oral glucose-lowering agents if capillary FPG levels were > 5.5 mmol/l
No clear effect on achieve two consecutive HbA1c levels <or= 6.5%1.7×
Reported higher greater increase in weight, no range given+1.90
randomisedthe abstract, start to end
… receiving glargine: (i) were 1.68 times more likely to achieve two consecutive HbA1c levels <or= 6.5% (95% CI 1.00-2.83; P = 0.049); (ii) reduced their HbA1c by 1.55 vs. 1.25% (P = 0.005), achieving adjusted means of 7.0 vs. 7.2% (P = 0.0007); (iii) had lower FPG (P = 0.0001), non-high-density lipoprotein (HDL) cholesterol (P = 0.02) and triglycerides (P = 0.02); (iv) had greater increases in treatment satisfaction (P = 0.045); and (v) had a 1.9-kg greater increase in weight …
← favours treatmentfavours comparator →
could be chanceNo interval given · direction only, strength unknown
Achieve two consecutive HbA1c levels <or= 6.5%evening insulin glargine plus self-titration by 1 unit/day if the fasting plasma glucose (FPG) was > 5.5 mmol/l vs conventional therapy with physician adjustment of oral glucose-lowering agents if capillary FPG levels were > 5.5 mmol/l
RR 1.681.00–2.83
Greater increase in weightevening insulin glargine plus self-titration by 1 unit/day if the fasting plasma glucose (FPG) was > 5.5 mmol/l vs conventional therapy with physician adjustment of oral glucose-lowering agents if capillary FPG levels were > 5.5 mmol/l
1.9
InsulinDiet, exercise & lifestyleGlycemic controlBody weight & composition
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