Trial reportThe British journal of ophthalmology2006
Viscocanalostomy versus trabeculotomy ab externo in primary congenital glaucoma: 1-year follow-up of a prospective controlled pilot study.
Trial report in The British journal of ophthalmology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Surgical interventions for primary congenital glaucoma.The Cochrane database of systematic reviews · 2020Pooled it
- Surgical interventions for primary congenital glaucoma.The Cochrane database of systematic reviews · 2015Pooled it
- Viscocanalostomy combined with trabeculotomy and mitomycin C in the treatment of primary congenital glaucoma.International journal of ophthalmology · 2017Article
- Surgical Outcomes of Trabeculotomy in Newborns with Primary Congenital Glaucoma.Chinese medical journal · 2016Article
- A review of the diverse genetic disorders in the Lebanese population: highlighting the urgency for community genetic services.Journal of community genetics · 2015Article
- Childhood glaucoma surgery in the 21st century.Eye (London, England) · 2014Review
- Surgical management in primary congenital glaucoma: four debates.Journal of ophthalmology · 2013Article
- Clinical effect of improved viscocanalostomy for the treatment of primary congenital glaucoma.International journal of ophthalmology · 2012Article
- A new manner of reporting pressure results after glaucoma surgery.Clinical ophthalmology (Auckland, N.Z.) · 2012Article
- Long-term surgical outcomes of primary congenital glaucoma in China.Clinics (Sao Paulo, Brazil) · 2009Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo study the effectiveness of viscocanalostomy in patients with primary congenital glaucoma of the isolated trabecular dysgenesis category and compare it with trabeculotomy ab externo.
methodsEight patients with bilateral primary congenital glaucoma were enrolled in the study. After establishing the diagnosis, the more severely affected eye was randomly selected to undergo either trabeculotomy ab externo or viscocanalostomy, whereas the second eye underwent the other surgery 2 weeks after the first. The patients were examined on day 1, week 1, week 4 and thereafter every 4 weeks. Intraocular pressure (IOP) and corneal diameter measurements were obtained at week 1, month 6 and at the last reported follow-up. The paired-sample's Student's t test was applied for statistical analysis.
resultsThe mean (standard deviation (SD)) follow-up period was 12.5 (1.86) months. Preoperative IOP of eyes undergoing trabeculotomy (34.0 (2.6) mm Hg) and that of eyes undergoing viscocanalostomy (32.3 (4.1) mm Hg) showed no significant difference (p>0.1). A drop in IOP was noted in both groups at week 1, month 6 and at the last follow-up visit (p<0.001). Similarly, a decrease in the postoperative vertical and horizontal corneal diameters was noted in the two study groups.
conclusionViscocanalostomy proved to be as effective as trabeculotomy ab externo in lowering IOP. Moreover, it is likely to be a good surgical alternative with a higher long-term success rate in eyes with more aggressive disease.
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