Evidence map›Paper›PMID 16836628›Full record

Trial reportJournal of general internal medicine2006

Improving depression care in patients with diabetes and multiple complications.

Leslie S Kinder, Wayne J Katon, Evette Ludman, Joan Russo, Greg Simon, Elizabeth H B Lin, Paul Ciechanowski, Michael Von Korff, Bessie Young

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Collaborative care for depression and anxiety problems.The Cochrane database of systematic reviews · 2012
    Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Severe Depressive Episode with Psychotic Symptoms and Type 2 Diabetes: A 2010-2017 Longitudinal Study.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  10. Article
  11. Article
  12. Anxiety and diabetes: Innovative approaches to management in primary care.Experimental biology and medicine (Maywood, N.J.) · 2016
    Review
  13. Article
  14. Article
  15. Article
  16. The comorbidity of diabetes mellitus and depression.The American journal of medicine · 2008
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Leslie S KinderHealth Services Research and Development, Veterans Affairs Puget Sound Health Care System, Seattle, WA 98101, USA. lskinder@stanfordalumni.org
Wayne J Katon
Evette Ludman
Joan Russo
Greg Simon
Elizabeth H B Lin
Paul Ciechanowski
Michael Von Korff
Bessie Young

Funding

RANDOMIZED TRIAL OF LIAISON PSYCHIATRY IN PRIMARY CARER01MH041739 · NIMH · UNIVERSITY OF WASHINGTON · PI KATON, WAYNE J · 1987 to 2010
$6.6M
Depression-Diabetes Care Disparities, Adverse OutcomesR01MH073686 · NIMH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI VON KORFF, MICHAEL R · 2005 to 2008
$1.8M
POPULATION BASED PSYCHIATRIC INTERVENTION--PRIMARY CAREK02MH001643 · NIMH · UNIVERSITY OF WASHINGTON · PI KATON, WAYNE J · 1999 to 2003
$484k
NIMH NIH HHS MH01643NIMH NIH HHS MH073686NIMH NIH HHS MH4-1739NIMH NIH HHS R01 MH073686
6 · The paper itself

Abstract

backgroundDepression is common in patients with diabetes, but it is often inadequately treated within primary care. Competing clinical demands and treatment resistance may make it especially difficult to improve depressive symptoms in patients with diabetes who have multiple complications.

objectiveTo determine whether a collaborative care intervention for depression would be as effective in patients with diabetes who had 2 or more complications as in patients with diabetes who had fewer complications.

designThe Pathways Study was a randomized control trial comparing collaborative care case management for depression and usual primary care. This secondary analysis compared outcomes in patients with 2 or more complications to patients with fewer complications. PATIENTS: Three hundred and twenty-nine patients with diabetes and comorbid depression were recruited through primary care clinics of a large prepaid health plan. MEASUREMENTS: Depression was assessed at baseline, 3, 6, and 12 months with the 20-item depression scale from the Hopkins Symptom Checklist. Diabetes complications were determined from automated patient records.

resultsThe Pathways collaborative care intervention was significantly more successful at reducing depressive symptoms than usual primary care in patients with diabetes who had 2 or more complications. Patients with fewer than 2 complications experienced similar reductions in depressive symptoms in both intervention and usual care.

conclusionPatients with depression and diabetes who have multiple complications may benefit most from collaborative care for depression. These findings suggest that with appropriate intervention depression can be successfully treated in patients with diabetes who have the highest severity of medical problems.

Indexed as

AdultAgedCooperative BehaviorDepressive DisorderDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansMaleMiddle AgedPsychiatric Status Rating Scales

Identifiers

PMID16836628
PMCPMC1831638

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.