Trial reportJournal of general internal medicine2006
Cost-effectiveness of a disease management program for major depression in elderly primary care patients.
Trial report in Journal of general internal medicine, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 5 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Selection and reporting of usual care comparators when designing primary care trials of complex health interventions: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Pooled it
- Elusive search for effective provider interventions: a systematic review of provider interventions to increase adherence to evidence-based treatment for depression.Implementation science : IS · 2018Pooled it
- Pooled it
- The estimation of utility weights in cost-utility analysis for mental disorders: a systematic review.PharmacoEconomics · 2013Pooled it
- Does GP training in depression care affect patient outcome? - A systematic review and meta-analysis.BMC health services research · 2012Pooled it
- Primary care management of major depression in patients aged > or =55 years: outcome of a randomised clinical trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2008Trial
- Cost effectiveness of telecare management for pain and depression in patients with cancer: results from a randomized trial.General hospital psychiatryTrial
- Review
- Article
- Cost-effectiveness of a transitional pharmaceutical care program for patients discharged from the hospital.PloS one · 2017Article
- The depression treatment cascade in primary care: a public health perspective.Current psychiatry reports · 2012Review
- Analysis of decisions made in meta-analyses of depression screening and the risk of confirmation bias: a case study.BMC medical research methodology · 2012Article
- Clinical effectiveness of using an integrated model to treat depressive symptoms in veterans affairs primary care clinics and its impact on health care utilization.The primary care companion for CNS disorders · 2011Article
- The effect of the COACH program (Continuity Of Appropriate pharmacotherapy, patient Counselling and information transfer in Healthcare) on readmission rates in a multicultural population of internal medicine patients.BMC health services research · 2010Article
- Depression in primary care: encouragement and caution for the business case.Journal of general internal medicine · 2006Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMajor depression is common in older adults and is associated with increased health care costs. Depression often remains unrecognized in older adults, especially in primary care.
objectiveTo evaluate the cost-effectiveness of a disease management program for major depression in elderly primary care patients compared with usual care.
designEconomic evaluation alongside a cluster randomized-controlled trial.
participantsConsecutive patients of 55 years and older were screened for depression using the Geriatric Depression Scale and the PRIME-MD was used for diagnosis.
interventionsGeneral practitioners in the intervention group received training on how to implement the disease management program consisting of screening, patient education, drug therapy with paroxetine, and supportive contacts. General practitioners in the usual care group were blind to the screening results. Treatment in this group was not restricted in any way. MEASUREMENTS: Severity of depression, recovery from depression, and quality of life. Resource use measured over a 12-month period using interviews and valued using standard costs.
resultsDifferences in clinical outcomes between the intervention and usual care group were small and statistically insignificant. Total costs were 2,123 dollars in the intervention and 2,259 dollars in the usual care group (mean difference -136 dollars, 95% confidence interval: -1,194 dollars; 1,110 dollars). Cost-effectiveness planes indicated that there were no statistically significant differences in cost-effectiveness between the 2 groups.
conclusionsThis disease management program for major depression in elderly primary care patients had no statistically significant relationship with clinical outcomes, costs, and cost-effectiveness. Therefore, based on these results, continuing usual care is recommended.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.