Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2006
Randomised controlled trial of near-patient testing for glycated haemoglobin in people with type 2 diabetes mellitus.
Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus.Diabetes care · 2011Guideline
- [Out-patient determination of glycosylated haemoglobin in the monitoring and control of diabetes mellitus: systematic review of the literature].Atencion primaria · 2008Pooled it
- The cost-effectiveness of point of care testing in a general practice setting: results from a randomised controlled trial.BMC health services research · 2010Trial
- HbA1c measurement using capillary blood in epidemiological studies: a scoping review of technologies and approaches.BMC endocrine disorders · 2026Article
- Point-of-Care HbA1c in Clinical Practice: Caveats and Considerations for Optimal Use.Diabetes care · 2024Review
- Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus.Diabetes care · 2023Review
- Guidelines and Recommendations for Laboratory Analysis in the Diagnosis and Management of Diabetes Mellitus.Clinical chemistry · 2023Article
- How point-of-care HbADiabetic medicine : a journal of the British Diabetic Association · 2020Article
- Performance of Point-of-Care Testing Compared with the Standard Laboratory Diagnostic Test in the Measurement of HbA1c in Indonesian Diabetic and Nondiabetic Subjects.Journal of diabetes research · 2020Article
- Understanding the adoption and use of point-of-care tests in Dutch general practices using multi-criteria decision analysis.BMC family practice · 2019Article
- Impact of HbA1c Testing at Point of Care on Diabetes Management.Journal of diabetes science and technology · 2017Review
- Economic Evidence and Point-of-Care Testing.The Clinical biochemist. Reviews · 2013Review
- Primary care diagnostic technology update: point-of-care testing for glycosylated haemoglobin.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- The Evidence to Support Point-of-Care Testing.The Clinical biochemist. Reviews · 2010Review
- How usual is usual care in pragmatic intervention studies in primary care? An overview of recent trials.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010Article
- Near-patient testing in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTight glycaemic control in people with type 2 diabetes can lead to a reduction in microvascular and possibly macrovascular complications. The use of near-patient (rapid) testing offers a potential method to improve glycaemic control.
aimTo assess the effect and costs of rapid testing for glycated haemoglobin (HbA1c) in people with type 2 diabetes. DESIGN OF STUDY: Pragmatic open randomised controlled trial.
settingEight practices in Leicestershire, UK.
methodPatients were randomised to receive instant results for HbA1c or to routine care. The principal outcome measure was the proportion of patients with an HbA1c <7% at 12 months. We also assessed costs for the two groups.
resultsOf the 681 patients recruited to the study 638 (94%) were included in the analysis. The mean age at baseline was 65.7 years (SD = 10.8 years) with a median (interquartile range) duration of diabetes of 4(1-8) years. The proportion of patients with HbA1c < 7% did not differ significantly between the intervention and control groups (37 versus 38%, odds ratio 0.95 [95% confidence interval = 0.69 to 1.31]) at 12 months follow up. The total cost for diabetes-related care was 390 UK pounds per patient for the control group and 370 UK pounds for the intervention group. This difference was not statistically significant.
conclusionNear-patient testing for HbA1c alone does not lead to outcome or cost benefits in managing people with type 2 diabetes in primary care. Further research is required into the use of rapid testing as part of an optimised patient management model including arrangements for patient review and testing.
Indexed as
Identifiers
16834877PMC1872061W1978499107What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.