ReviewCritical care (London, England)2006
Hyperglycaemia in critically ill patients: marker or mediator of mortality?
Review in Critical care (London, England), 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 64 citations in OpenAlex.
- Diabetes-specific enteral nutrition formula in hyperglycemic, mechanically ventilated, critically ill patients: a prospective, open-label, blind-randomized, multicenter study.Critical care (London, England) · 2015Trial
- Early versus late intravenous insulin administration in critically ill patients.Intensive care medicine · 2008Trial
- Stress hyperglycemia is associated with poor prognosis in critically ill patients with cardiogenic shock.Frontiers in endocrinology · 2024Article
- Stress hyperglycemia is associated with poor outcome in critically ill patients with pulmonary hypertension.Frontiers in endocrinology · 2024Article
- The Role of Nondiabetic Hyperglycemia in Critically Ill Patients with Acute Ischemic Stroke.Journal of clinical medicine · 2022Article
- In-Hospital Mortality and Glycemic Control in Patients with Hospital Hyperglycemia.The review of diabetic studies : RDS · 2021Article
- A Machine-Generated View of the Role of Blood Glucose Levels in the Severity of COVID-19.Frontiers in public health · 2021Article
- Article
- Effects of pH, lactate, hematocrit and potassium level on the accuracy of continuous glucose monitoring (CGM) in pediatric intensive care unit.Italian journal of pediatrics · 2015Article
- Comparative performance assessment of point-of-care testing devices for measuring glucose and ketones at the patient bedside.Journal of diabetes science and technology · 2015Article
- Monitoring of Hypocalcaemia & Hyperglycemia predictive consequences of Thyroidectomy.International archives of medicine · 2014Article
- Back to basics in sepsis treatment: critically ill patients need intensive care.Critical care (London, England) · 2014Article
- Diabetes and hemoglobin a1c as risk factors for nosocomial infections in critically ill patients.Critical care research and practice · 2013Article
- Glucose dysmetabolism and prognosis in critical illness.Internal and emergency medicine · 2009Review
- Current status of tight blood sugar control.Current infectious disease reports · 2008Article
- Blood glucose levels should be considered as a new vital sign indicative of prognosis during hospitalization.Diabetes & metabolic syndromeReview
- Clinical and epidemiological study of stress hyperglycemia among medical intensive care unit patients in Central India.Indian journal of endocrinology and metabolismArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute hyperglycaemia has been associated with complications, prolonged intensive care unit and hospital stay, and increased mortality. We made an inventory of the prevalence and prognostic value of hyperglycaemia, and of the effects of glucose control in different groups of critically ill patients. The prevalence of hyperglycaemia in critically ill patients, using stringent criteria, approaches 100%. An unambiguous negative correlation between hyperglycaemia and mortality has been described in various groups of critically ill patients. Although the available evidence remains inconsistent, there appears to be a favourable effect of glucose regulation. This effect on morbidity and mortality depends on patient characteristics. To be able to compare results of future studies involving glucose regulation, better definitions of hyperglycaemia (and consequently of normoglycaemia) and patient populations are needed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.